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Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Itraconazole is potentially effective for treating invasive aspergillosis, but more research is needed.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Apoptosis is essential for human skin development and forming a functional epidermis.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

PGD2 stops hair growth and is higher in bald men with AGA.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.