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    Did you mean Interleukin-1?
    Glossary Interleukin-1

    protein that regulates immune and inflammatory responses

    Interleukin-1 (IL-1) is a type of protein called a cytokine that plays a crucial role in the body's immune and inflammatory responses. It helps regulate immune reactions by promoting the activation of white blood cells and the production of other inflammatory molecules. Elevated levels of IL-1 are often associated with conditions like autoimmune diseases and chronic inflammation.

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    1. Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress International journal of biological sciences · 2023 · 2 citations
    2. Interleukin 6: insights to its function in skin by overexpression in transgenic mice. Proceedings of the National Academy of Sciences · 1992 · 221 citations
    3. Dermatologic Changes Associated With Interleukin 2 Administration JAMA · 1987 · 123 citations
    4. Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes 2001 · 90 citations
    5. The many faces of interleukin-17 in inflammatory skin diseases 2016 · 77 citations
    6. WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis Burns & Trauma · 2022 · 56 citations
    7. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    8. The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population Gene · 2013 · 42 citations
    9. Testosterone stimulates proliferation and inhibits interleukin‐6 production of normal and hereditary gingival fibromatosis fibroblasts Oral Microbiology and Immunology · 2002 · 39 citations
    10. Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture Journal of interferon & cytokine research · 1997 · 38 citations
    11. Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages Annals of the Rheumatic Diseases · 2014 · 36 citations
    12. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    13. Interleukin-1β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP Journal of Investigative Dermatology · 1997 · 33 citations
    14. Interleukin-10-deficient Mice Are Less Susceptible to the Induction of Alopecia Areata Journal of Investigative Dermatology · 2002 · 31 citations
    15. Recurrence of Pemphigus Vulgaris Associated With Interleukin 2 Therapy Archives of Dermatology · 1994 · 25 citations
    16. Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans Journal of Interferon & Cytokine Research · 2014 · 22 citations
    17. Alopecia Diffusa while Using Interleukin-17 Inhibitors against Psoriasis Vulgaris Case Reports in Dermatology · 2019 · 20 citations
    18. Minoxidil downregulates Interleukin-1 alpha gene expression in HaCaT cells International Journal of Trichology · 2018 · 16 citations
    19. Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2016 · 16 citations
    20. Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata 2021 · 14 citations
    21. Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity Advances in Dermatology and Allergology · 2020 · 14 citations
    22. Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps Mediators of inflammation · 2019 · 14 citations
    23. Influence of interleukin‐1α on androgen receptor expression and cytokine secretion by cultured human dermal papilla cells Experimental Dermatology · 2006 · 14 citations
    24. Genetic analysis of interleukin 18 gene polymorphisms in alopecia areata Journal of Clinical Laboratory Analysis · 2018 · 12 citations
    25. Interleukin 6 and STAT3 regulate p63 isoform expression in keratinocytes during regeneration Experimental Dermatology · 2015 · 11 citations
    26. A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations Gene · 2013 · 11 citations
    27. Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice Inflammation and Regeneration · 2023 · 7 citations
    28. <i>Trichophyton tonsurans</i>‐induced kerion celsi with decreased defensin expression and paradoxically increased interleukin‐17A production The Journal of Dermatology · 2019 · 7 citations
    29. Interleukin-15 and Tumor Necrosis Factor-α in Iraqi Patients with Alopecia Areata Dermatology Research and Practice · 2023 · 6 citations
    30. To evaluate the role of interleukin-6 in alopecia areata Journal of the Pakistan Medical Association · 2024 · 5 citations