January 2026 in “Scientific Reports” In this study, researchers found that sesamin, a component of sesamum, modulated the AR-MAPK-Wnt signaling pathway in DHT-stimulated HaCaT keratinocytes, demonstrating potential multi-target activity against molecular events in androgenetic alopecia.
June 2020 in “Journal of Investigative Dermatology” This symposium reviewed advances in understanding complex skin diseases through genetics and genomics, emphasizing the role of regulatory signals and environmental components in disease development, but reports no new clinical findings.
6 citations
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October 2013 in “Yichuan” This review summarizes the role of miRNAs in epidermal and hair follicle development, highlighting their potential impact on understanding gene regulatory networks and applications in disease treatment and molecular breeding.
April 2026 in “International Journal of Engineering Research and Science & Technology” This study reports that an Explainable AI-based hair health prediction system using a novel hybrid model outperformed traditional machine learning methods, achieving high accuracy in predicting key factors and providing personalized recommendations.
1 citations
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June 2024 in “Skin Research and Technology” This study found that secretory proteins in DFCM play crucial roles in regulating nerve restoration by forming significant protein interaction networks during the wound repair process.
3 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that enhanced wound healing in oral mucosa involves a SOX2-regulated transcriptional network which includes increased expression of keratin K75, and interaction of K75 with the LINC complex may play a crucial role in promoting rapid wound repair.
May 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, human dermal fibroblast-conditioned medium was found to contain numerous proteins involved in wound repair and hair regeneration, with identified proteins forming interaction networks linked to key signaling pathways like epidermal growth factor receptor and transforming growth factor-β.
January 2024 in “Wiadomości Lekarskie” This presentation will review neural networks and artificial intelligence basics, then explore their recent developments and applications in medical care, particularly in decision-making processes to enhance diagnostic accuracy and treatment strategies, ultimately improving patient outcomes in critical situations, as reported in this source.
11 citations
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June 2020 in “FEBS Journal” This review discusses the regulation of myeloid cell networks in barrier tissues and how various factors influence immune homeostasis, but it reports no new experimental results.
5 citations
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June 2022 in “Biophysical Journal” This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.
7 citations
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January 1981 in “Springer eBooks” This model study describes how interactions between hair keratin and various materials alter hair's physical and mechanical properties by affecting noncovalent bonds.
August 2026 in “ChemRxiv” This review explores the convergence of functional biomaterials, biosensing, and AI technologies in bioengineering, highlighting applications in cancer modeling and regenerative medicine, while addressing challenges like biofouling and dataset integration.
24 citations
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March 2018 in “Pigment Cell & Melanoma Research” This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.
January 2024 in “Wiadomości Lekarskie” In this study, the integration of artificial intelligence in medicine was discussed, highlighting its potential to enhance diagnostic processes, optimize therapies, and provide advanced patient monitoring despite challenges like data inconsistency and limited model transparency.
January 2026 in “Vestnik dermatologii i venerologii” This review found that AI in dermatology shows high diagnostic accuracy comparable to experienced clinicians, but integration into clinical practice faces challenges requiring further research.
January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.
December 2024 in “International Journal of experimental research and review” In this study, the integration of obesity-related features and machine learning techniques significantly enhanced cardiovascular disease detection, with the XGBoost classifier achieving a 74% accuracy rate and improved metrics compared to other models.
2 citations
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November 2025 in “Briefings in Bioinformatics” In this study, the researchers performed a comparative analysis of drug-target interaction data from multiple databases to refine drug repurposing strategies, revealing potential associations between drug characteristics and therapeutic groups, and predicting repositioning opportunities for FDA-approved drugs across major cancer types.
May 2026 in “ACS Catalysis” In this study, researchers using QM/MM simulations identified key molecular motions and residue interactions in the enzyme SRD5A2 that significantly influence its catalytic efficiency, demonstrating that specific residues play critical roles in stabilizing transition states and reducing activation barriers.
May 2026 in “International Journal of Molecular Sciences” This study suggests that hydroxytyrosol may influence inflammation and oxidative stress pathways in androgenetic alopecia, particularly through interaction with the PTGS2 gene, warranting further experimental validation.
252 citations
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March 1998 in “Developmental dynamics” This study suggests that fibroblast growth factors FGF-4, FGF-8, and FGF-9 may play redundant roles as signals in epithelial-mesenchymal interactions during multiple stages of tooth development in mice.
July 2024 in “Journal of Investigative Dermatology” This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.
160 citations
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June 2008 in “American Journal Of Pathology” This review discusses the effects of the epidermal growth factor receptor system on skin biology and pathology, relying on animal models to analyze roles in cellular processes, wound healing, and tumorigenesis, but reports no new results.
356 citations
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March 2012 in “Trends in Plant Science” This review discusses the crosstalk between auxin and ethylene in seedling growth and development, emphasizing how ethylene modulates auxin's effects across different tissues.
610 citations
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April 2014 in “Nature Reviews Immunology” This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.
149 citations
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July 2017 in “PLoS Biology” This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
June 2024 in “British Journal of Dermatology” This study observed that many patients with afro-textured hair feel their dermatologists do not fully understand their hair loss unless they also have such hair, and highlighted a need for more targeted patient information resources and education for dermatologists to improve care and patient satisfaction.
September 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that lymphatic vessels play a crucial role in hair follicle growth and regeneration in mice by connecting hair follicles and expanding during stem cell activation.
3 citations
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June 2017 in “Methods” This study used computational modeling to identify key genes and miRs involved in cardiac aging, finding a strong relationship supported by literature and some experimental validation in aged mouse hearts.
2 citations
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June 2021 in “Notulae Botanicae Horti Agrobotanici Cluj-Napoca” This review examines the role of root hair specification and nutrient acquisition in plants, emphasizing the need for further genetic research to understand the mechanisms influencing root hair development and growth.