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Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

No clear link between androgen receptor variation and hair loss, but more research needed.

Genetically modifying a bacteria and changing its growth conditions significantly increased the production of a chemical called dipicolinic acid.

The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

VDR regulation varies by tissue and is crucial for its biological functions.

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.