2 citations
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August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that electrospun membranes with aligned surface topography enhanced wound healing and hair follicle regeneration while modulating the immune response in a mouse skin wound model.
2 citations
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March 2019 in “Journal of Histochemistry and Cytochemistry” This study found that NNAT is localized in both undifferentiated and differentiated cells across various rat tissues and has cell-specific intracellular localization, suggesting distinct functional roles.
2 citations
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November 2017 in “Histochemistry and Cell Biology” This study observed varying levels of polyamines in different compartments of rat hair follicles, indicating their potential involvement in hair growth, especially in the matrix and inner root sheath layers.
2 citations
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March 2011 in “Veterinary Dermatology” This study identified fibroblast growth factor 18 in various components of canine hair follicles and other tissues, but found no significant differences in its presence across seasons, body regions, or sexes in beagle dogs.
2 citations
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January 2001 in “Biomedical Research” This study found that peptidylarginine deiminase type III and trichohyalin are coincidentally expressed in the infant rat hair follicle, but trichohyalin deimination occurs after their expression during development.
2 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” In this study, proteolytic enzymes applied to mice skin caused severe degeneration in hair follicles, including detachment of stem cells from their niche, suggesting potential impairment of stem cell function.
2 citations
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January 1993 This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.
1 citations
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October 2017 in “Frontiers in Physiology” This article proposes a hypothesis that KRT75, a protein found in hair follicles, was evolutionarily co-opted by ameloblasts during the development of prismatic enamel in synapsids, but reports no new results.
1 citations
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July 2017 in “Microscopy and Microanalysis” In this study using C57BL/6 mice, researchers found that iron oxide nanoparticles permeated skin primarily through hair follicles and sebocytes, with absorption increasing over time.
1 citations
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January 2017 The document outlines criteria to identify and differentiate neoplasms based on follicular characteristics.
1 citations
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January 2013 in “China Animal Husbandry & Veterinary Medicine” This study found a strong positive correlation between vascular endothelial growth factor expression and microvessel density in the hair follicles of Liaoning cashmere goats during different fetal periods.
1 citations
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July 2012 in “Nasza Dermatologia Online” This case report suggests that immune responses, along with hair traction, may play a role in the etiology of central centrifugal cicatricial alopecia.
1 citations
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January 1993 in “Skin Pharmacology and Physiology” This study found that an extracellular calcium binding site gradient exists in mouse vibrissa and human scalp follicles, but is not significantly affected by hair growth-altering drugs or epidermal growth factor.
1 citations
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October 1988 in “Clinics in dermatology” This paper explores cell kinetics in human hair follicles, focusing on the proliferation rates of keratinocytes and dermal papilla cells, but provides no new experimental findings.
October 2024 in “International Journal of Comprehensive Veterinary Research.” In this study, researchers examined the skin of neonatal rabbits and found that most hair follicles were in the terminal stage, with hair shafts protruding through the epidermis, but noted the absence of sweat glands.
December 2023 in “International Journal of Medical Arts” In this study, researchers observed significant morphological and histological differences in transplanted hair follicles compared to native donor follicles post-FUE hair transplantation for androgenetic alopecia, highlighting substantial variations in sebaceous gland and root sheath degeneration at the recipient site.
February 2023 in “International journal of molecular sciences” This study used infrared spectral imaging to show for the first time the distribution of glypican-4 and glypican-6 in hair follicles across different growth phases, highlighting the potential of this technique for studying alopecia.
January 2023 in “Karger Kompass. Dermatologie” This review discusses the complexity of identifying hair follicle antigens involved in alopecia areata and reports no new clinical results, emphasizing the need for further research on autoantigen identity.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that TSPyV T antigens can disrupt normal cell differentiation and proliferation in hair follicles and interfollicular epidermis, possibly contributing to trichodysplasia spinulosa pathology.
Trichodysplasia spinulosa can occur after a heart transplant due to immunosuppressive drugs.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
This review discusses loose anagen hair syndrome in children, characterized by non-scarring alopecia and increased hair shedding, and reports no new results; topical minoxidil may be used as a treatment.
October 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study investigated NNAT expression in embryonic and postnatal rat tissues, finding its localization in both undifferentiated and differentiated cells across tissues such as the pancreas, tongue, and testis.
September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This case report suggests that in African-American patients, the histology of Central Centrifugal Cicatricial Alopecia may resemble lichen planopilaris, indicating a potential diagnostic challenge.
April 2017 in “Journal of Investigative Dermatology” This study found that hair follicle matrix progenitors differentiate into various layers asynchronously, with early progenitors forming the companion layer and later progenitors generating the inner root sheath and hair shaft.
April 2017 in “Journal of Investigative Dermatology” This study identified that in mice, sweat gland development is directed by mesenchymal signals that suppress SHH-production, while in humans, this occurs through a BMP spike in embryonic development.
September 2016 in “Journal of dermatological science” The researchers reported that the OVOL1-OVOL2 axis may play a role in hair follicle differentiation and tumorigenesis, and OVOL1 and OVOL2 are potential diagnostic markers for pilomatricoma and pilomatrix carcinoma.
April 2016 in “Journal of Investigative Dermatology” CD73 may regulate hair growth and could be targeted for hair growth treatments.
January 2015 in “Chinese Veterinary Science” This study observed distinct changes in the ultrastructure of Hexi cashmere goat hair follicles throughout the year, highlighting stages with specific cellular and structural characteristics.