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    Glossary Inner Hair Cells

    specialized sensory cells in the cochlea converting sound to signals

    Inner Hair Cells (IHCs) are specialized sensory cells located in the cochlea of the inner ear. They play a crucial role in hearing by converting sound vibrations into electrical signals, which are then transmitted to the brain via the auditory nerve. Unlike outer hair cells, which primarily amplify sound, IHCs are directly responsible for sending auditory information to the central nervous system.

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    1. CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024 · 1 citations
    2. eLife assessment: CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024
    3. Reviewer #2 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024
    4. CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024
    5. Reviewer #1 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024
    6. Zinc deficiency triggers hearing loss by reducing ribbon synapses of inner hair cells in CBA/N mice Biochemical and Biophysical Research Communications · 2024
    7. Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells Journal of the Association for Research in Otolaryngology · 2025
    8. Exosomes mediate sensory hair cell protection in the inner ear Journal of Clinical Investigation · 2020 · 49 citations
    9. The SYP123-VAMP727 SNARE complex is involved in the delivery of inner cell wall components to the root hair shank in Arabidopsis bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    10. A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle Journal of Investigative Dermatology · 2002 · 86 citations
    11. Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss Molecular Medicine Reports · 2017 · 2 citations
    12. Cytochemistry of Trichohyalin Granules: A Possible Role for Cornification of Inner Root Sheath Cell in the Hair Follicle The Journal of Dermatology · 1989 · 4 citations
    13. Structural features of the α-type filaments of the inner root sheath cells of the guinea pig hair follicle Biochemistry · 1978 · 24 citations
    14. Reviewer #3 (Public Review): CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells 2024
    15. Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea Research Square (Research Square) · 2022
    16. Melatonin promotes proliferation of Inner Mongolia cashmere goat hair follicle papilla cells through Wnt10b Genomics · 2024
    17. Experimental Studies of Inner Ear Hair Cell Regeneration. Equilibrium Research · 1995
    18. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear Neuroscience Bulletin · 2023 · 26 citations
    19. Isolation and properties of inner sheath cells of hair follicles Experimental Cell Research · 1964 · 26 citations
    20. Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle. PubMed · 1990 · 44 citations
    21. Author response: Generation of inner ear hair cells by direct lineage conversion of primary somatic cells 2020 · 1 citations
    22. A Low Dose of Rapamycin Promotes Hair Cell Differentiation by Enriching SOX2+ Progenitors in the Neonatal Mouse Inner Ear Organoids. PubMed · 2024
    23. Some observations on the proteins of the inner root sheath cells of hair follicles Biochimica et Biophysica Acta · 1958 · 34 citations
    24. Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles Archives of Dermatological Research · 2008 · 9 citations
    25. Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear Developmental neurobiology · 2010 · 11 citations
    26. A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea eLife · 2019 · 15 citations
    27. Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea 2019
    28. Decision letter: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea 2019
    29. 1390 Active hair growth is fuelled by conveyor-belt like differentiation of germinative layer cells Journal of Investigative Dermatology · 2023
    30. Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice Journal of Investigative Dermatology · 2000 · 31 citations