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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The Rotterdam Study aims to understand various diseases in older adults.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Different types of skin cells play specific roles in development, healing, and cancer.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Hair loss affects self-esteem and quality of life; treatments can help.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Myrtle has various health benefits and potential for medicine development.

Latanoprost can make eyelashes longer, thicker, and darker.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Androgens can cause hair growth in some areas and hair loss on the scalp.