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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Special fiber materials boost the healing properties of certain stem cells.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

CDP is crucial for lung and hair follicle cell development.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.