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APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.

Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.

Blood type affects COVID-19 infection rates differently in Europe and Africa.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

COVID-19 and vaccines cause various skin reactions and highlight the need for dermatologists in managing these issues and addressing vaccine distribution disparities.

Angelica Dahurica extract helps reduce hair loss and improve hair growth and scalp condition.

Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.

The document concludes that Telogen Effluvium is a hair loss disorder that can be assessed with the modified wash test and may be treated with clobetasol foam, with patient management being important.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Nirmatrelvir/Ritonavir treatment may lead to a weaker immune response to COVID-19, but doesn't affect the chance of rebound.

Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.

Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Biologics for severe asthma have known side effects, but some new risks need more study.

Thuja orientalis and Thuja occidentalis essential oils have medicinal properties useful for developing treatments with antimicrobial and bioactive effects.

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

Testosterone's effects on COVID-19 are unclear and need more research.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

Spirulina extract and C-phycocyanin may help heal wounds.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

A man developed a benign tumor at his COVID-19 vaccination site, which was successfully removed with surgery.

Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.