research Hair Whitening in a Patient with Psoriasis on Adalimumab Reversed After Switching to Ixekizumab
Switching from adalimumab to ixekizumab improved a patient's psoriasis and reversed hair whitening.
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research Exuberant Tufted Folliculitis
Tufted folliculitis is common in patients with folliculitis decalvans.
research The Effects of Hair Regrowth with Intravenous Immunoglobulin (IVIG) Therapy: Two Case Reports
IVIG therapy was linked to hair regrowth in two patients with hair loss, but it's not recommended due to its risks and costs.
research Pachyonychia Congenita: Sporadic Onset With Mutation Analysis
A boy with Pachyonychia congenita has a confirmed gene mutation, highlighting the need for a local genetic database in India.
research Telogen Effluvium: A Late Complication of Influenza A Sw H1N1 Pneumonia
Hair loss can happen after severe H1N1 flu but usually grows back in 4 months.
research Trichoscopy II: Cicatricial Alopecia
Trichoscopy helps tell apart Lichen planopilaris and Frontal fibrosing alopecia from other hair loss conditions.
research Highlights of Hair India 2012: The Second International Congress of Trichology
Hair India 2012 was a successful international event focused on combating fake trichology practices and discussing various hair health topics.
research Clinical Approach to Focal Hairless Patch with Dermoscopy
Dermoscopy helps diagnose different hair loss conditions, and characteristics vary among ethnicities and individual cases.
research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
The study investigated the pathogenesis of lichen planopilaris (LPP), a chronic inflammatory disease causing permanent hair loss, by analyzing scalp biopsies from 42 adult patients. It found that LPP is characterized by the collapse of immune privilege in the hair follicle's epithelial stem cell niche, known as the bulge. This collapse was evidenced by increased expression of MHC class I and II and a Th1-biased cytotoxic T cell response, alongside increased proliferation and apoptosis of epithelial hair follicle stem cells (eHFSCs). The findings suggested that interferon-γ (IFNγ) plays a significant role in this process, indicating that LPP may be an autoimmune disease. The study proposed that protecting or restoring immune privilege in the bulge could be a therapeutic strategy for managing this treatment-resistant form of cicatricial alopecia.
research An Overview of Alopecia Areata: Etiopathogenesis, Diagnosis, and Management
Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.
research Linear Morphea with Evidence of Hair Regrowth
Topical treatments led to hair regrowth in a man with linear morphea.
research Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Post-Menopausal Frontal Fibrosing Alopecia
The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.
research Treatment of Subacute and Chronic Discoid Lupus Erythematosus with Intensive Calcium Pantothenate Therapy
The study investigated the effects of intensive calcium pantothenate therapy on 14 patients with subacute and chronic discoid lupus erythematosus, particularly affecting the scalp. Patients received 400 mg of calcium pantothenate daily, with no additional therapies except a bland covering paste. The treatment showed improvement in the inflammatory phase of the disease, especially in subacute cases, and was well-tolerated without adverse reactions, unlike other treatments such as sodium paramino-benzoate. In some cases, therapy was paused to assess its impact, and calcium lactate was tested as a substitute without success. Only one patient developed new lesions during the treatment, and some required additional phenol cauterization.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multicenter Study of the International Dermoscopy Society
The study concludes that early diagnosis of Frontal Fibrosing Alopecia is important, as it is often found in postmenopausal women, may be related to Lichen Planopilaris, and eyebrow hair loss is a common sign.
research Alopecia Secondary to Anti-Tumor Necrosis Factor-Alpha Therapy
Anti-TNF therapy can cause hair loss and skin issues.
research Effect of an Oral Probiotic Formula on Scalp and Facial Skin Condition, Glucose, and Lipid Metabolism
Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
research Alopecia Areata in an Adolescent With Inflammatory Bowel Disease
A girl with Crohn's disease developed hair loss from her medication, which improved with treatment but later returned.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research Hair Loss in Patients with Inflammatory Bowel Disease
People with Inflammatory Bowel Disease often lose hair due to stress, medication side effects, or lack of nutrients, and treatment depends on the specific cause.
research Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases
Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.
research Frequency and Associated Factors of Hair Loss Among Patients With Inflammatory Bowel Disease
Hair loss is common in IBD patients, and some medications may lower the risk.
research Primary Cicatricial Alopecia and Inflammatory Bowel Disease – Is There a Link?
Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.
research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Treatment-Resistant Giant Unilateral Bowen’s Disease of the Scalp Responding to Radiotherapy
Radiotherapy was effective for treating a large scalp plaque of Bowen's disease when other treatments failed.
research Inflammatory Loops in the Epithelial-Immune Microenvironment of the Skin and Skin Appendages in Chronic Inflammatory Diseases
Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.
research Current Problems in Dermatology: Diseases of the Hair and Scalp, Vol. 12
The book "Diseases of the Hair and Scalp" has outdated information and confusing content, but may still offer some insights.
research Regulatory T Cells in Inflammatory Skin Disease: From Mice to Humans
Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
research Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn’s Disease: Dramatic Improvement After Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies
Stopping the medication infliximab and starting new treatments helped a woman's hair grow back and improved her scalp condition.