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    Did you mean Inflammasome?
    Glossary Inflammasome

    complex of proteins detecting harmful stimuli, triggering inflammation

    An inflammasome is a complex of proteins within cells that plays a crucial role in the immune system by detecting harmful stimuli, such as pathogens or stress signals. When activated, it triggers an inflammatory response by promoting the release of pro-inflammatory cytokines, which help to fight infections but can also contribute to inflammatory diseases if not properly regulated.

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    Research 30 of 555

    1. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    2. The crosstalk between PTEN ‐induced kinase 1‐mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata Experimental Dermatology · 2023 · 6 citations
    3. Inflammasome Proteins Are Reliable Biomarkers of the Inflammatory Response in Aneurysmal Subarachnoid Hemorrhage Cells · 2024 · 4 citations
    4. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    5. 1330 The possible role of PTEN-induced kinase 1-mediated mitophagy by regulating inflammasome activation in the pathogenesis of alopecia areata 2023
    6. Baricitinib Attenuates IFN-γ and Polyinosinic:polycytidylic Acid‒Induced Mitochondrial Damage and Inflammasome Activation in Human Keratinocytes Journal of Investigative Dermatology · 2022
    7. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    8. 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma Journal of Investigative Dermatology · 2016 · 1 citations
    9. Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair Burns & Trauma · 2026
    10. 1117 PX-12 inhibits NLRP3 inflammasome activation to treat psoriasis Journal of Investigative Dermatology · 2023
    11. Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease Pharmaceuticals · 2023 · 17 citations
    12. Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products Frontiers in Pharmacology · 2024 · 18 citations
    13. NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium Cell Communication and Signaling · 2019 · 50 citations
    14. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    15. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    16. Cell death in skin function, inflammation, and disease Biochemical Journal · 2022 · 12 citations
    17. Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction? Experimental dermatology · 2021 · 9 citations
    18. Genotoxic Agents: An Unexpected Effect on Healthy Epithelia Developmental cell · 2020 · 2 citations
    19. Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology Hair transplant forum international · 2012 · 1 citations
    20. Pyroptosis in Alopecia Areata: Synthesizing Emerging Hypotheses and Charting a Path to New Therapies Biomedicines · 2025
    21. Co-editors’ Messages Hair transplant forum international · 2013
    22. Revealing biological mechanisms of skin pigment recovery during treatment in vitiligo patients: A proteomic analysis Journal of Investigative Dermatology · 2026
    23. The many faces of interleukin-17 in inflammatory skin diseases 2016 · 77 citations
    24. Novel TMEM173 Mutation and the Role of Disease Modifying Alleles Frontiers in immunology · 2019 · 47 citations
    25. Characterization of novel TMEM173 mutation with additive IFIH1 risk allele bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 1 citations
    26. 642 Uncovering the role of UV exposure history and genetics in determining skin sun damage Journal of Investigative Dermatology · 2016 · 1 citations
    27. 646 SOX4 is essential for melanoma tumorigenesis Journal of Investigative Dermatology · 2016
    28. Sponsored Lecture 2 : Global aspects of acne treatment: current & future benefits 프로그램북(구 초록집) · 2015
    29. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    30. Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress Antioxidants · 2025