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    Glossary AIM2 inflammasome

    protein complex detecting foreign DNA, triggering immune responses

    The AIM2 inflammasome is a protein complex in the immune system that detects foreign DNA inside cells, such as from viruses or bacteria. When AIM2 senses this DNA, it activates a series of responses that lead to inflammation and the destruction of the infected cell, helping to protect the body from infections.

    Research 10 of 58

    1. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    2. Inflammasome Proteins as Biomarkers of Injury and Disease Springer eBooks · 2014
    3. Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles Scientific reports · 2017 · 22 citations
    4. Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair Burns & Trauma · 2026
    5. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice Journal of Immunology · 2015 · 59 citations
    6. Inflammasome Proteins Are Reliable Biomarkers of the Inflammatory Response in Aneurysmal Subarachnoid Hemorrhage Cells · 2024 · 4 citations
    7. Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products Frontiers in Pharmacology · 2024 · 18 citations
    8. Inflammation in androgenetic alopecia and hair loss: linking neurosciences-endocrinology-dermatology Hair transplant forum international · 2012 · 1 citations
    9. Cell death in skin function, inflammation, and disease Biochemical Journal · 2022 · 12 citations
    10. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
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