46 citations
,
December 2003 in “Advances in neonatal care” This article reviews fetal scalp hair formation and related disorders but reports no new research results.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” In this study, gender-affirming hormonal treatment was associated with increased hair growth, acne, and alopecia prevalence in transgender individuals assigned female at birth, while opposite dermatological changes were observed in those assigned male at birth.
192 citations
,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study suggests that metformin may be more effective than Dianette in treating moderate to severe hirsutism in women with PCOS, while also reducing markers of insulin resistance.
343 citations
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October 2015 in “Endocrine Practice” This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.
30 citations
,
October 2014 in “Journal of The American Academy of Dermatology” This article reviews current treatment options for acne, hirsutism, and androgenetic alopecia in women with PCOS, recommending individualized and multidisciplinary approaches, but reports no new clinical results.
16 citations
,
May 2019 in “Hormone and Metabolic Research” This systematic review found insufficient evidence to support protective effects of selenium on polycystic ovary syndrome complications, despite some studies suggesting it may reduce insulin resistance and dyslipidemia.
13 citations
,
December 2006 in “Journal of experimental animal science” This study found that injecting interferon gamma into C3H/HeJ mice did not alter the frequency or onset of alopecia areata, suggesting the protein alone does not trigger the disease.
4 citations
,
November 2017 in “Scientific Reports” This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.
August 2024 in “Qucosa (Saxon State and University Library Dresden)” In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.
288 citations
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June 2009 in “Human reproduction update” This review examines various methods for assessing hair growth in women, highlighting the usefulness of the mFG visual scoring method for diagnosing hirsutism despite its limitations.
5 citations
,
June 2015 in “International Journal of Women's Dermatology” This article reviews hirsutism from an endocrine perspective and reports no new clinical findings.
January 2025 in “PLoS ONE” This study found that ING5 knockout mice are prone to developing lymphomas and severe dermatitis, suggesting ING5 plays a role in tumor suppression and stem cell maintenance in vivo.
26 citations
,
June 2005 in “Journal of The American Academy of Dermatology” In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.
2 citations
,
July 2025 in “Acta Pharmacologica Sinica” Isoginkgetin reduces inflammation in cells by blocking NF-κB activation.
February 2024 in “IntechOpen eBooks” In this study, the use of "ProFecund Ino," a myo-inositol-based treatment for women with PCOS, was associated with a 38% pregnancy rate, and when combined with reproductive techniques, it significantly increased pregnancy chances.
22 citations
,
April 1998 in “Dermatologic Clinics” This article reviews the therapeutic use of interferons and other cytokines in various viral, tumorous, and inflammatory diseases, discussing their biological effects and potential future applications without presenting new experimental results.
1 citations
,
April 2024 in “Journal of Cutaneous Pathology” This article presents a case of spontaneous, recurrent necrotizing infundibular crystalline folliculitis in the inguinal region and suggests unknown etiology possibly linked to microbiome and sebaceous gland dysfunction.
19 citations
,
September 2006 in “Journal of Pediatric Gastroenterology and Nutrition” In this case study, a 12-year-old girl with severe Crohn colitis achieved impressive clinical and endoscopic remission after receiving infliximab and azathioprine as first-line treatment, suggesting potential benefits of early intensive therapy.
20 citations
,
January 2017 in “Experimental Dermatology” In this study, deleting the Igf1 receptor in specific skin cells of mice affected hair follicle cycling but not overall skin health, suggesting Igf1r's role in hair cycle regulation through Bmp-4 activation.
January 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that targeting both hormonal and immune pathways improved treatment outcomes in androgenetic alopecia patients with an under-recognized inflammatory component called PIILIF, which may contribute to treatment resistance.
5 citations
,
April 2020 in “Journal of Mind and Medical Sciences” This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.
16 citations
,
October 2013 in “Irish Veterinary Journal” This case study describes the successful use of recombinant feline interferon-omega in managing feline chronic gingivostomatitis syndrome in cats with type II diabetes, where long-acting corticosteroids are contraindicated.
November 2023 in “Deleted Journal” In this study, the researchers found no superiority of combining 308-nm excimer laser with intralesional corticosteroid over corticosteroid alone for treating frontal fibrosing alopecia, and reported side effects such as erythema and postinflammatory hyperpigmentation in both treatment groups.
1 citations
,
January 2020 This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
2 citations
,
July 2004 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that multiple treatments combining NIR laser phototherapy with ICG significantly reduced inflammation and improved skin condition in acne without side effects.
December 2017 in “The Sri Lanka Journal of Dermatology” This study reports a case where treatment with the TNF alpha inhibitor infliximab successfully resolved refractory alopecia universalis in a 41-year-old woman.
July 2022 in “British Journal of Dermatology” This study found that epidermal growth factor receptor inhibitors used in cancer treatment induce a distinct inflammatory response in hair follicles, marked by immune privilege collapse and upregulation of inflammatory pathways.
December 2025 in “Fertility and Sterility” Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.
October 2025 in “Biomolecules” This study found that prolonged intermittent fasting in diet-induced obese mice led to increased levels of inositol monophosphates in white adipose tissue, improved insulin sensitivity, and reduced body weight and fat mass, suggesting a novel metabolic adaptation mechanism.
Infliximab was effective in treating a scalp condition that did not respond to other treatments.