18 citations
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January 1976 in “Clinical Science” This study found that minoxidil significantly reduced supine diastolic pressure in 94% of patients with severe essential hypertension within 4 weeks, but some patients experienced side effects such as increased hair growth and fatigue.
November 2025 in “Medicina” This study found that patients with alopecia areata had a lower heart rate compared to healthy controls and showed disease-severity-related changes in body composition, though the clinical importance of these findings is still unclear.
1 citations
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January 2012 in “International Journal of Trichology” Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
July 2024 in “Heart Lung and Circulation” There may be a link between hair loss and heart disease in women, but more research is needed.
343 citations
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December 2008 in “Endocrine Reviews” This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.
162 citations
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April 2016 in “The Lancet Diabetes & Endocrinology” This review discusses the effects of testosterone therapy for transgender men, noting desired outcomes and potential risks, but reports no new research findings; the authors highlight a lack of high-quality data due to various study limitations.
45 citations
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March 2015 in “Clinical Endocrinology” This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.
24 citations
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January 2015 in “International Journal of Trichology” This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.
15 citations
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August 2021 in “Reviews in endocrine and metabolic disorders” This review discusses hypopituitarism's bidirectional relationship with COVID-19 due to metabolic comorbidities and pituitary risks, but it reports no new clinical results.
January 2015 in “Springer eBooks” This chapter reviews polycystic ovary syndrome's clinical features, highlighting diagnostic criteria and management strategies, and reports no new findings; the authors emphasize the need for targeted treatment approaches.
December 2021 in “International Journal of Research in Dermatology” This study found a higher prevalence of metabolic syndrome among young male patients with androgenic alopecia compared to age-matched controls.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
6 citations
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January 2021 in “Journal of The American Academy of Dermatology” This letter discusses adverse events related to low-dose oral minoxidil for alopecia, highlighting age-related risks and stressing the importance of contraindication awareness with no new clinical results presented.
August 2025 in “Chronobiology International” In this study, college students with an evening chronotype were found to be at greater risk for androgenetic alopecia, potentially due to altered circadian rhythms as indicated by shifts in heart rate patterns and clock gene expression in hair follicles.
January 2023 in “Brazilian Journals Editora eBooks” Passiflora incarnata may help with anxiety and sleep issues but has side effects; teleconsultation for heart failure can improve quality of life; increased screen time for children during the pandemic led to more clinical complaints; older and severely affected COVID-19 patients are more likely to have long-term symptoms.
44 citations
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August 1996 in “Drugs & Aging” Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
October 1997 in “Baylor University Medical Center Proceedings” Obesity in the U.S. is largely influenced by diet and exercise, certain medications can improve heart procedures and hair growth, and major teaching hospitals have better patient outcomes.
5 citations
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January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.
11 citations
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May 1990 in “Journal of Dermatological Science” In this animal study, topical diazoxide treatment led to increased hair thickness and follicle growth in bald stumptailed macaques without causing notable systemic side effects.
1 citations
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January 2023 in “Brazilian Journals Editora eBooks” Children's screen time increased during the pandemic, causing various health issues.
June 1996 in “Irish Journal of Medical Science (1971 -)” This study found a statistically significant increase in glycosylated hemoglobins among patients with adult-acquired panhypopituitarism undergoing long-term GH replacement therapy, with two developing diabetes requiring treatment.
1 citations
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January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
5 citations
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March 1992 in “PubMed” In this study, researchers found that arsenic transfer to induced hair in rats increased sharply at first and then more gradually, correlating significantly with arsenic levels in key organs.
2 citations
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August 2014 in “PubMed” This case report details a woman with postural orthostatic tachycardia syndrome who experienced notable dermatological symptoms, including evanescent hyperemia, which improved with the use of an oral angiotensin II type 1 receptor antagonist.
6 citations
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October 1979 in “Chest” This study found that minoxidil significantly reduces systemic blood pressure and vascular resistance in patients with hypertension, but does not alter pulmonary vascular resistance or exacerbate pulmonary hypertension.
May 2022 in “Голова и шея.” The study found that experimental inflammation from nasal septum surgery in rats caused a shifts in autonomic nervous system balance, with sympathetic dominance and parasympathetic suppression, normalizing after one week.
2 citations
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October 2020 in “Más dermatología” Choose between topical and oral minoxidil for hair growth based on personal tolerance and side effects.
January 2004 in “Chinese Journal of Blood Purification” This study found that minoxidil is highly effective in managing severe hypertension in hemodialysis patients without affecting renal function, though it may cause hair growth.
1 citations
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May 2022 in “Голова и шея.” This study found that septoplasty simulation in rats led to decreased exploratory behavior and anxiety, suggesting a link between postoperative stress and changes in the hippocampal region.
40 citations
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November 2021 in “npj Regenerative Medicine” In this study, spiny mice showed superior cardiac recovery after myocardial infarction compared to other mouse strains, with enhanced myocardial preservation and functional stabilization.