January 2016 in “Experimental Dermatology” New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
47 citations,
December 2011 in “Experimental Dermatology” CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
November 2022 in “Journal of Investigative Dermatology” Dandruff is linked to changes in the immune system of hair follicles and skin.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
30 citations,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
21 citations,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
1 citations,
January 2021 in “Skin appendage disorders” A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
July 2023 in “The Egyptian Journal of Hospital Medicine ” Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” ILC1-like cells can cause alopecia areata by attacking hair follicles.
September 2024 in “Journal of the American Academy of Dermatology” Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.
November 2022 in “Journal of Investigative Dermatology” Cell-based therapy using specific immune cells may help treat alopecia areata by promoting hair regrowth.
November 2023 in “Journal of Investigative Dermatology” γδTregs can protect hair follicles from alopecia areata and may help regrow hair.
79 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
26 citations,
September 2013 in “Journal of Dermatological Science” Serum granulysin levels can indicate the activity and prognosis of alopecia areata.
8 citations,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
1 citations,
June 2006 in “Experimental dermatology” The conclusion suggests that early signs of hidradenitis suppurativa may start in the hair follicle, with genetic and immune factors playing a role, highlighting the need for more research on the hair follicle's immune system.
124 citations,
January 2012 in “Journal of Allergy and Clinical Immunology” Endocannabinoids help control mast cell activity in human skin.
21 citations,
June 2011 in “Investigative Ophthalmology & Visual Science” Hair follicles could help develop eye treatments by studying immune responses.
4 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
March 2024 in “International Journal of Cosmetic Science” Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.