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    Glossary Immune-Mediated

    immune system mistakenly attacks the body's own cells

    Immune-mediated refers to conditions or diseases that are caused by abnormal activity of the immune system, where it mistakenly attacks the body's own cells and tissues. This can lead to various health issues, such as inflammation, tissue damage, and organ dysfunction. Examples include autoimmune diseases like rheumatoid arthritis and alopecia areata, where the immune system targets hair follicles, leading to hair loss.

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    Research 30 of 1000+

    1. The emergence of Alopecia Areata is not dependent on perforin-mediated cytolysis The Journal of Immunology · 2024
    2. Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing 2020 · 34 citations
    3. 120 Identification of post-translationally modified trichohyalin epitopes responsible for triggering autoimmunity in alopecia areata Journal of Investigative Dermatology · 2023
    4. Anti-Aging Medicine for Hair International journal of cell science & molecular biology · 2018
    5. Immunohistochemical localization of TGF‐β in alopecia areata 1997
    6. A Case Report of Association between Canine Hypothyroidism and Diabetes International Journal of Zoology and Animal Biology · 2023
    7. Alopecia Areata The New England Journal of Medicine · 2012 · 421 citations
    8. The Pathogenesis of Primary Cicatricial Alopecias The American Journal of Pathology · 2010 · 150 citations
    9. The Review on Alopecia Areata : A Comprehensive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    10. The Review on Alopecia Areata : A Comprehensive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    11. The Review On "Alopecia Areata: A Compressive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    12. The Review On "Alopecia Areata: A Compressive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    13. The Review on Alopecia Areata : A Comprehensive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    14. The Review on Alopecia Areata : A Comprehensive Review of Pathogenesis, Diagnosis, Clinical Pattern and Remedies Zenodo (CERN European Organization for Nuclear Research) · 2025
    15. EVALUATION OF THE ROLE OF CXCL12 IN CASES OF ALOPECIA AREATA ALEXMED ePosters · 2025
    16. Deciphering the Complex Immunopathogenesis of Alopecia Areata International Journal of Molecular Sciences · 2024 · 45 citations
    17. Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche Science Immunology · 2024 · 21 citations
    18. Pathomechanisms of immune-mediated alopecia International Immunology · 2019 · 45 citations
    19. 0977 Pathogenic hallmarks of primary lymphocyte-mediated scarring alopecia revealed by single nuclear and spatial multiomics Journal of Investigative Dermatology · 2025
    20. Pathophysiology of Alopecia Areata in the Pediatric Patient Pediatric Dermatology · 2025 · 5 citations
    21. Lymphocytes, neuropeptides, and genes involved in alopecia areata Journal of Clinical Investigation · 2007 · 286 citations
    22. Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors InTech eBooks · 2018 · 2 citations
    23. Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance Frontiers in Medicine · 2026
    24. The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review Nutrients · 2022 · 40 citations
    25. Immune modulation of hair follicle regeneration npj Regenerative Medicine · 2020 · 29 citations
    26. Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review Dermatology and therapy · 2021 · 16 citations
    27. The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds Cells · 2023 · 9 citations
    28. Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration Genes & Diseases · 2025 · 1 citations
    29. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002 · 114 citations
    30. Low-level laser therapy in immune-mediated skin disease: a narrative review Medical lasers · 2022