May 1991 in “Current problems in dermatology” Skin issues can indicate immune system problems.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
115 citations,
September 2000 in “The Lancet” Early hair loss may indicate risk of insulin resistance.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
16 citations,
February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
7 citations,
January 2019 in “Australasian Journal of Dermatology” A genetic marker linked to a type of hair loss was found in most patients studied.
6 citations,
July 2018 in “Advances in Clinical and Experimental Medicine” Different body parts have varying levels of certain hair follicle markers.
5 citations,
April 2014 in “Journal of Obstetrics and Gynaecology Research” Young Indian women with PCOS have a higher risk of heart disease, not linked to thyroid function but to higher levels of certain fats and homocysteine.
June 2023 in “Research Square (Research Square)” Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
33 citations,
April 2011 in “Journal of Veterinary Internal Medicine” Long-term fluticasone treatment does not harm the immune system in horses with heaves.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
21 citations,
July 2016 in “Gynecological Endocrinology” Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
21 citations,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
16 citations,
July 2020 in “International Journal of Molecular Sciences” Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.
15 citations,
April 2017 in “Cell Stem Cell” Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
9 citations,
November 2020 in “Medical Hypotheses” Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
8 citations,
June 2016 in “Clinical Chemistry” PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
4 citations,
December 2017 in “American Journal of Dermatopathology” Naked hair shafts are significantly associated with scarring hair loss and may help diagnose it, especially when multiple are found.
1 citations,
July 2015 in “Cytokine” Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
1 citations,
June 2011 in “Journal of Genetics” Some human genetic markers work for genetic studies in pig-tailed and stump-tailed macaques, which can help in their conservation.
April 2018 in “Journal of Investigative Dermatology” Researchers found that the Leptin receptor is a consistent marker for hair follicle dermal cells, which may help future hair research.
April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
21 citations,
January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
9 citations,
November 2011 in “Cytokine” Finasteride helps reduce lung inflammation and damage after trauma and infection.
7 citations,
December 2014 in “Journal of dermatology” Hair shaft miR-221 levels can help detect malignant melanoma.
June 2024 in “Research Square (Research Square)” Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
April 2021 in “Journal of Investigative Dermatology” The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.
November 2020 in “Postepy Dermatologii I Alergologii” Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.
438 citations,
October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
47 citations,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.