Birth Outcomes of Infants Born to Mothers with Alopecia Areata: A Nationwide Population-Based Study in Korea

January 2025 in “ Acta Dermato Venereologica ”

Jung Won Shin, Taeuk Kang, Heather Swan, Kyungho Paik, Chang‐Hun Huh, Hyun Jung Kim

TLDR Mothers with alopecia areata have a higher risk of adverse birth outcomes.

This nationwide population-based study in Korea examined 45,328 children born to mothers with alopecia areata (AA) and 4,703,253 controls to assess the impact of maternal AA on birth outcomes. The study found that infants born to mothers with AA had a significantly higher risk of preterm birth, low birthweight, and Caesarean section birth compared to controls. Additionally, there was an increased risk of congenital malformations, particularly affecting the urinary and musculoskeletal systems, in infants born to mothers with AA. The findings suggest that maternal AA is associated with an increased risk of adverse birth outcomes.

View this study on medicaljournalssweden.se →

Discuss this study in the Community →

Research cited in this study

5 / 5 results

Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity

research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity

57 citations, April 2019 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

research Alopecia Areata: A Review of Disease Pathogenesis

191 citations, May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

research Altered Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells from Patients with Alopecia Areata

12 citations, March 2016 in “BBA clinical”

Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.

research Genetic Basis of Alopecia Areata

40 citations, October 2012 in “Dermatologic clinics”

More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.

research Alopecia Areata Update

391 citations, January 2010 in “Journal of The American Academy of Dermatology”

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Related Community Posts Join

6 / 1000+ results

community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

in Chat 55 upvotes 1 year ago

The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 8 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 832 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If follicles became miniaturized and haven’t grown in 3 years, are they dead ?

in Chat 2 years ago

Hair loss and its potential treatments, such as minoxidil, finasteride, RU58841, dermarolling, and supplements. It discusses whether miniaturized follicles can be revived to grow again or must shed for new growth to appear.

community 22F. Should I even bother getting a biopsy? Is there any point?

7 upvotes 8 years ago

A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

community Recovery from a severe case of Telogen Effluvium. Nov 2023 - February 2024 (m22, Oral min & fin)

in Progress Pictures 315 upvotes 1 year ago

A user recovered from severe Telogen Effluvium using 1mg finasteride and 2.5mg oral minoxidil within four months. Another user regained 80% hair density with finasteride and minoxidil over two years, and is now trying dutasteride.

Related Research

1 / 1 results

research Serum Zinc Concentration in Patients With Alopecia Areata

October 2023 in “Acta dermato-venereologica (Print)”

People with severe hair loss have lower zinc levels in their blood.