1 citations,
March 2021 in “Skin health and disease” Better hair loss models needed for research.
30 citations,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
13 citations,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
2 citations,
September 2023 in “Curēus” Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
70 citations,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
138 citations,
June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
August 2022 in “International Journal of Molecular Sciences” DNA methylation controls lncRNA2919, which negatively affects hair growth.
13 citations,
September 2010 in “Journal of Dermatological Science” Researchers made a cell line that grows quickly and can help with hair growth research.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
16 citations,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
Researchers improved mouse skin cell culture methods and created a similar immortal cell line, but need to clarify their methods and benefits.
Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.
The review suggested the study needed to clarify its purpose, compare with non-immortalized cells, and provide more details on methods.
15 citations,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
April 2012 in “Cancer research” Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
88 citations,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
13 citations,
February 2023 in “Aging” A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
8 citations,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
3 citations,
January 2023 in “Physiological Research” Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
4 citations,
February 2022 in “PeerJ” Hair follicle stem cell transplants can reverse liver cirrhosis by blocking harmful cell activation.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
26 citations,
March 2013 in “Journal of Biomedical Materials Research Part A” Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
4 citations,
December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
7 citations,
January 2021 in “Evidence-based complementary and alternative medicine” Porphyra-334 may help reduce wrinkles and promote hair growth.
68 citations,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.