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Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

New effective scar treatments are urgently needed due to the current options' limited success.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Stem cell niches support, regulate, and coordinate stem cell functions.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Liposomes could improve how skin care products work but are costly and not very stable.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.