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Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Iron deficiency common in women, not always linked to hair loss; more research needed.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Intralesional triamcinolone acetonide is the most effective treatment for localized alopecia areata.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Early balding men may have insulin resistance, but lifestyle changes can help.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Higher BMI links to worse hair loss in Taiwanese men.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Iron deficiency is not a significant cause of hair loss in women.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

The conclusion suggests a possible link between iron levels and hair health in women, recommending further research on iron supplementation for hair loss.

Genetic marker rs12558842 strongly linked to male hair loss.