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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

New genes and pathways are important for testosterone production and male sexual development.

Early diagnosis and treatment of TPP can prevent complications.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Long COVID affects over half of COVID-19 survivors, causing a range of symptoms like fatigue and neurological issues, with no specific treatment yet.

Children with severe ichthyosis and growth failure rarely have nutritional deficiencies or gastrointestinal issues, but may experience chronic dehydration.

The patient's long-term symptoms were due to Sheehan's syndrome, which improved with hormone therapy.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

The document discusses a condition causing hair loss after surgery and a type of rosacea affecting the nose, with treatments including surgery and laser therapy.

Finasteride causes sperm production decrease in Mesocricetus auratus.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

A woman with anorexia developed gout from self-induced vomiting.

Hair dye chemicals can cause serious health problems, including kidney damage.

Plasma gel and PRP treatments improve skin and hair with minimal side effects.

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

Bariatric surgery patients need careful before and after surgery care for safety and long-term health.

The Blood Glucose Management Service improved patient safety and outcomes in managing blood sugar in hospitalized patients.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Fluorescent light energy may help treat skin infections in dogs with calcinosis cutis.