Search
for

    Did you mean Keratinocyte Hyperproliferation?
    Glossary Keratinocyte Hyperproliferation

    rapid and excessive growth of skin cells

    Keratinocyte hyperproliferation refers to the rapid and excessive growth of keratinocytes, which are the primary cells found in the outer layer of the skin. This condition is often associated with skin disorders like psoriasis, where the skin cells multiply too quickly, leading to thick, scaly patches.

    Related Terms

    Sort by

    Research 30 of 985

    1. Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes Experimental Dermatology · 2000 · 58 citations
    2. No evidence for follicular keratinocyte hyperproliferation in acne lesions as compared to autologous healthy hair follicles Experimental Dermatology · 2018 · 7 citations
    3. Dandruff Is a Low‐Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin‐17‐Producing T Cells, and N‐Acyl Ethanolamines Immunity Inflammation and Disease · 2026
    4. Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro Differentiation · 1987 · 135 citations
    5. Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia Developmental biology · 1999 · 69 citations
    6. Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair Laboratory investigation · 2008 · 28 citations
    7. Enhancing 1α-Hydroxylase Activity with the 25-Hydroxyvitamin D-1α-Hydroxylase Gene in Cultured Human Keratinocytes and Mouse Skin Journal of Investigative Dermatology · 2001 · 18 citations
    8. 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion 2022
    9. 876 Manipulation of stem cell divisional behavior: Selectively promoting asymmetric and symmetric keratinocyte divisions in vitro Journal of Investigative Dermatology · 2017
    10. Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair 2000 · 113 citations
    11. Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations 2011 · 41 citations
    12. CtBP1 Overexpression in Keratinocytes Perturbs Skin Homeostasis Journal of Investigative Dermatology · 2013 · 9 citations
    13. Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell death and differentiation · 2011 · 76 citations
    14. The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function 2013 · 1 citations
    15. Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice Journal of Investigative Dermatology · 2024
    16. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    17. Abstract 5357: Targeting mTORC1 suppresses proliferation of keratinocyte stem cells and inhibits skin tumor promotion in mice Cancer research · 2014
    18. Cellular and molecular mechanisms of repair in acute and chronic wound healing British Journal of Dermatology · 2015 · 908 citations
    19. KERATINS AND SKIN DISORDERS Cell biology international · 1996 · 28 citations
    20. Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis International journal of molecular sciences · 2024 · 1 citations
    21. A two-phase model of skin epidermal stratification: lessons from centrosomes bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    22. High proliferation and delamination during skin epidermal stratification Nature Communications · 2021 · 51 citations
    23. Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency 2005 · 39 citations
    24. [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies]. PubMed · 1990 · 6 citations
    25. Genotoxic Agents: An Unexpected Effect on Healthy Epithelia Developmental cell · 2020 · 2 citations
    26. The RATIOnal Role of Polyamines in Epidermal Differentiation Journal of Investigative Dermatology · 2021
    27. Does Nicastrin Inadequacy Cause Melanocytotoxicity in Human Skin as in the Fish Counterpart? 2021
    28. 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury Journal of Investigative Dermatology · 2016
    29. 266 Myristoylphorbol Acetate (MPA) Enhances Metastasis Via Up-regulation of Eph A2 Transcription Activity European journal of cancer · 2012
    30. The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling Development · 2011 · 134 citations