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The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Accurate diagnosis of pseudolymphomatous folliculitis is crucial to avoid mistaking it for more serious conditions.

Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Big chain pharmacies in Pennsylvania charge significantly more for generic BPH medications than independent pharmacies, but independent pharmacies have more regional price variation.

Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.

Endurance exercise may help BPH by lowering hormones and inflammation.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.

Chlormadinone acetate is useful for birth control and treating various hormonal issues.

Male pattern baldness may be an early sign of noncancerous prostate enlargement.

5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Castration significantly reduces prostate size and BPH symptoms.

Many patients with lower urinary tract symptoms also have undiagnosed erectile dysfunction, which improves with treatment.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Hyperandrogenism, often causing excessive hair growth and acne, can be treated with methods like weight reduction, hair removal, various medications, and in the case of acne, topical treatments.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.

Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

Most women with hirsutism have normal hormone levels and can be treated with cosmetic methods; obesity and PCOS are common causes, and treatments depend on the underlying issue.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.