16 citations
,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
4 citations
,
June 2019 in “Revista brasileira de ginecologia e obstetrícia” This article discusses the prevalence of hirsutism in women and highlights that many cases exhibit normal androgen levels, suggesting a need for broader diagnostic approaches.
October 2024 in “Journal of the Endocrine Society” This case report details a diagnostic challenge in a postmenopausal woman with severe hyperandrogenism where distinguishing between adrenal and ovarian causes was complicated by elevated 17-OH Progesterone and asymmetric ovarian enlargement; pending surgical pathology is expected to guide further management.
March 2016 in “The Journal of Urology” This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” This review discusses how androgens may regulate wound healing and inflammation, noting that testosterone appears to inhibit healing and promote inflammation, but it reports no new clinical results.
27 citations
,
February 2005 in “Journal of Cellular Biochemistry” This study found that rat male costochondral chondrocytes, unlike female chondrocytes, respond to testosterone through metabolism to dihydrotestosterone, which shows a maturation-state dependent effect in male growth plate cells.
April 2019 in “Journal of the Endocrine Society” This study found that androgen-regulated genes in hidradenitis suppurativa skin lesions are strongly linked to innate immunity pathways, indicating a potential connection between androgen signaling and inflammation in this condition.
9 citations
,
November 2013 in “Presse Medicale” This article discusses clinical features and treatment options for hyperandrogenism in women and does not report new findings, highlighting current practices in diagnosis and management.
September 2014 in “Springer eBooks” This review discusses how sex hormone levels and local steroid synthesis influence gender differences in aging skin, reporting no new clinical results.
1 citations
,
June 2008 in “The Journal of Urology” This letter to the editor references a study on using dihydrotestosterone gel before hypospadias surgery but itself contains no new findings.
1 citations
,
January 2009 in “CRC Press eBooks” This chapter discusses the increasing prevalence of overactive bladder in aging men, examining potential causes and treatment options, without reporting new clinical results.
October 2020 in “Проблемы эндокринологии” This review discusses the potential roles of androgens and antiandrogens in COVID-19 outcomes, noting unresolved questions about their effectiveness and safety for treatment.
98 citations
,
September 1981 in “Fertility and Sterility”
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.
April 2015 in “The FASEB Journal” In this study, perinatal androgen deprivation in male rats led to elevated estrogen levels and a lack of sexual motivation towards gonadally-intact female rats.
15 citations
,
September 2017 in “Dermatologic Surgery” This literature review found that chemical peels are effective for treating various skin conditions in men, such as acne, rosacea, and photodamage, and noted that men may require more treatments or stronger peels due to their skin's characteristics.
January 2016 in “AACE Clinical Case Reports” In this case report, an embryonal cell carcinoma of the testicle was associated with polycythemia and markedly elevated hormone levels without secondary sexual characteristics, which were restored after treatment.
April 2025 in “Sabuncuoglu Serefeddin Health Sciences” This study highlights the public health significance of androgenic-anabolic steroid use disorder, emphasizing health risks, societal effects, and the need for routine AAS analyses in forensic autopsies, especially in athlete deaths.
16 citations
,
February 2014 in “Iranian Red Crescent Medical Journal” This qualitative study revealed that women with PCOS often see themselves as less feminine, affected by symptoms like excess hair and irregular menstruation, which challenged their gender roles.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of an estradiol-secreting adrenocortical carcinoma in a 58-year-old male, causing feminization and Marie-Antoinette syndrome, with potential paraneoplastic aortitis.
This study analyzed Yul Brynner's star image in 1950s Hollywood, highlighting how his distinct physical presence and flexible ethnic portrayals influenced his cinematic appeal, while examining the interplay of his unique performance style with biographical tales.
October 2020 in “Medicine - Programa De Formación Médica Continuada Acreditado” This review discusses female hyperandrogenism, focusing on its diagnosis, differential diagnoses, and individualized treatment approaches to improve patient health and quality of life, and reports no clinical results.
1 citations
,
January 2013 in “CU Scholar (University of Colorado Boulder)” This review discusses the historical practice of postmortem mutilation in Early America, highlighting its role in intercultural communication, racialized violence, and the construction of racial identities; it reports no new empirical findings.
3 citations
,
March 2022 in “Transgender Health” This review examines existing plastic surgery techniques for gender affirmation of the lower extremities, noting a lack of outcomes-based literature needed to establish best practices.
2 citations
,
August 2023 in “Journal of Endocrinological Investigation” In this study, researchers found that pregnant mice exposed to excessive androgen led to thinner ventricular walls and cardiac hypertrophy in offspring, suggesting that prenatal androgen exposure adversely affects cardiac health through reduced cardiomyocyte proliferation.
12 citations
,
October 2018 in “Aging male/The aging male” This study found that prostate cancer aggressiveness in men with obesity is associated with changes in age, BMI, testosterone, and estradiol levels, and that adipocyte-secreted molecules increase cancer cell aggressiveness in vitro.
October 2025 in “Journal of the Endocrine Society” This case report illustrates a rare instance of mixed germ cell tumor in the pituitary with hyperandrogenism, emphasizing the importance of thorough examination and hormone evaluation in identifying hormonal dysfunctions.
35 citations
,
January 2000 in “Dermatology” In this study, Norwegian men aged 20-50 who perceived themselves as having more hair loss reported greater dissatisfaction and concern about aging compared to those without hair loss.
March 2009 in “The Journal of Urology” This article discusses historical aspects of gender development, particularly related to the discovery of finasteride, and reports no new clinical results.
September 2006 in “Data Archiving and Networked Services (DANS)” This article discusses the testosterone and estradiol levels in men, examining their roles and suggesting the need for better understanding to differentiate between normal and abnormal levels related to androgen deficiency symptoms, without reporting new clinical results.