TLDR Finasteride helps treat hair loss and prostate issues by blocking a hormone.
The document discussed the discovery of finasteride, a medication that was significant in the treatment of conditions like benign prostatic hyperplasia and androgenetic alopecia. It explored the biological mechanisms by which finasteride worked, particularly its role in inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to hair loss and prostate growth. The article also touched upon the broader implications of hormonal changes, such as how certain conditions could lead to changes in sexual development, metaphorically described as "how girls become boys." This research contributed to a better understanding of hormonal therapies and their applications in urology and dermatology.
17 citations
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June 2012 in “Australasian Journal of Dermatology” Finasteride and low-dose dutasteride combo improves hair growth and reduces hair loss with no major side effects.
March 2025 in “Journal of Education Health and Sport” Finasteride can cause sexual and psychological side effects, but these usually reverse after stopping the medication.
33 citations
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January 2009 in “Journal of Cutaneous and Aesthetic Surgery” Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.
36 citations
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June 2014 in “PLOS ONE” Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
1 citations
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December 2017 in “Journal of The European Academy of Dermatology and Venereology” Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.
218 citations
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December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.