research Hidradenitis Suppurativa: An Androgen-Dependent Disorder
Hidradenitis suppurativa improves with antiandrogen therapy.
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research Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness
High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.
research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone
Spironolactone may help enlarge a small breast linked to Becker's nevus.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in Males
Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
research Bone vs. Fat: Embryonic Origin of Progenitors Determines Response to Androgen in Adipocytes and Osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research Antiandrogenic Activities of Glycyrrhiza Glabra in Male Rats
Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
research Activity of Type 1 5α-Reductase Is Greater in the Follicular Infrainfundibulum Compared with the Epidermis
The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
research Dermatosis Associated with Menopause
Menopause can cause skin issues, and seeing a dermatologist helps.
research Androgens and Hair: A Biological Paradox with Clinical Consequences
Androgens can both increase body hair and cause scalp hair loss.
research Serum Ferritin and Vitamin D Levels Should Be Evaluated in Patients With Diffuse Hair Loss Prior to Treatment
Check and treat low iron and vitamin D levels in people with hair loss.
research Androgens and the Menopause
Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Characterizing Dermatological Conditions in the Transgender Population: A Cross-Sectional Study
Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.
research Clinical and Phototrichogrammatic Evaluation of Estradiol Replacement Therapy on Hair Growth in Postmenopausal Japanese Women with Female Pattern Hair Loss: A Pilot Study
Hormone replacement therapy may improve hair growth in the frontal hairline of postmenopausal women with hair loss.
research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
Stress hormone CRF causes hair loss and inhibits hair growth in human cells.
research The Local Hypothalamic–Pituitary–Adrenal Axis in Cultured Human Dermal Papilla Cells
Stress hormone CRF causes hair loss and stops hair cell growth.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research The North American Menopause Society Recommendations for Clinical Care of Midlife Women
The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
research Biology of the Hair Follicle: The Basics
The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
research Melatonin
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Gender-Linked Differences in Human Skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Roles of Jumonji and Jumonji Family Genes in Chromatin Regulation and Development
Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.