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Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Certain gene variations might be linked to severe acne in women but not in men.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

The enzyme myo-inositol oxygenase is not linked to the cause of polycystic ovarian syndrome.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

A man with Isaac's syndrome affecting only one side of his body improved after immune system-targeted treatment.

Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Higher BPA levels may be linked to idiopathic hyperandrogenemia in women.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.