18 citations
,
November 2007 in “Annals of Surgery” Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
75 citations
,
January 2014 in “Korean Journal of Urology” This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.
1 citations
,
November 2007 in “Humana Press eBooks” This article reviews the differential diagnosis and management approaches for androgen excess disorders, highlighting the predominance of polycystic ovary syndrome as the underlying cause and reports no new clinical findings.
This chapter discusses how nanotechnology, through the use of metal nanoparticles and biocompatible carriers, along with antioxidants like curcumin, quercetin, and resveratrol, offers promising approaches for treating PCOS by reducing oxidative stress and inflammation, enhancing insulin sensitivity, and normalizing hormone levels.
August 2023 in “Journal of Clinical Medicine” This study found that metformin's effect on reducing prolactin levels is less pronounced in women with PCOS compared to control subjects, likely due to higher endogenous testosterone levels, despite improvements in insulin sensitivity in both groups after six months of treatment.
May 2019 in “Pakistan Journal of Pharmaceutical Sciences” This case report presented a female with PCOS treated with metformin who developed hyperuricemia, migraine, neurological and joint pain, and rheumatic fever, later showing a delayed hypersensitivity reaction to benzathine benzyl penicillin treatment.
November 2016 in “Hair transplant forum international” This article summarizes Dr. Alan Jacobs's presentation at the 2016 ISHRS World Congress but reports no new research findings.
39 citations
,
April 2001 in “Journal of The American Academy of Dermatology” This article reviews the side effects of topical latanoprost therapy, particularly the hypertrichosis and pigmentation changes of eyelashes and nearby skin, and reports no new clinical results.
This study reviews the use of natural products, like herbal extracts and essential oils, in treating male pattern baldness, noting their potential benefits compared to conventional therapies that may carry side effects or ethical concerns.
210 citations
,
November 2015 in “The Lancet HIV” This study observed that while PrEP was effective among transgender women if taken, adherence was low, especially among those at higher risk.
76 citations
,
November 2009 in “Medical Clinics of North America” This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
64 citations
,
August 2019 in “Circulation” This study found that men receiving enzalutamide and other androgen-deprivation therapies may be at increased risk for QT prolongation and torsades de pointes.
59 citations
,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
47 citations
,
April 2020 in “Dermatologic Therapy” This letter discusses the potential connection between androgenetic alopecia and COVID-19, suggesting a possible new therapy, but it reports no new results.
46 citations
,
January 1996 in “Journal of The American Academy of Dermatology” This study identified the presence of apoptotic or necrotic keratinocytes and hair shaft dystrophy as potential markers of hair loss in patients with HIV-1 infection.
42 citations
,
August 2013 in “International Journal of Women's Health” This review discusses the current therapeutic options for female pattern hair loss and emphasizes the need for managing patient expectations of permanent regrowth, reporting no new clinical results.
40 citations
,
January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
34 citations
,
October 2018 in “Journal of The American Academy of Dermatology” This review discusses hormone-modulating therapies for androgen-mediated cutaneous disorders in women but reports no new clinical results and highlights the need for more rigorous studies.
26 citations
,
June 2003 in “Obstetrics and gynecology clinics of North America” This review discusses the use of insulin-sensitizing agent metformin for treating PCOS in adolescents, noting potential benefits but emphasizing the need for more rigorous trials due to current study limitations.
20 citations
,
November 2019 in “Biomolecules” This study found that finasteride impaired stress reactivity and reduced exploratory and impulsive behaviors in rats, potentially by altering the hypothalamus-pituitary-adrenal axis function.
13 citations
,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.
6 citations
,
December 2020 in “Dermatological reviews” This review discusses the potential link between androgenic alopecia, androgens, and the severity of COVID-19, highlighting possible therapeutic targets but reports no new clinical results.
2 citations
,
May 2001 in “Current problems in dermatology” The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
1 citations
,
September 2022 in “Problems of Endocrinology” This review discusses sex differences in Parkinson's disease and highlights that while men are more frequently affected, androgen-modulating treatments have not yet proven effective for PD, though 5α-reductase inhibitors show potential for further study.
December 2023 in “Magna Scientia Advanced Research and Reviews” This study proposes that combining trazodone and clomiphene citrate could potentially restore libido synaptic circuits and treat post-finasteride syndrome, which involves persistent sexual dysfunction after discontinuing finasteride treatment.
August 2018 in “Ayurline: IJ-RIM” This review discusses the role of diet and lifestyle in managing alopecia and reports no new clinical results.
January 2017 in “Journal of Antivirals & Antiretrovirals” This retrospective study observed that breast cancer treatments disrupted normal blood counts and led to bone marrow suppression, highlighting the need for nutritional counseling to improve patient quality of life.
February 2013 in “Journal of The American Academy of Dermatology” Hair loss is a common side effect of hormone treatments for cancer.
April 1981 in “Postgraduate Medicine” This article reviews surgical hair replacement techniques for bald patients dissatisfied with hairpieces and reports that various options provide good results with minimal side effects, emphasizing the importance of frontal area design for a natural appearance.
December 1976 in “PubMed” This review discusses the histology of pilo-sebaceous follicles, androgen receptors, and various treatments for hirsutism and acne in women, but it reports no new clinical results.