Evaluation of the Hemogram of Breast Cancer Patients Treated by Therapeutic Protocol Based on Immunohistochemical Analysis: A Retrospective Study

    January 2017 in “ Journal of Antivirals & Antiretrovirals ”
    Nidda Saeed, Fahad Pervaiz, Sohail Manzoor, Muhammad Ali, Sara Saleem, Saliha Khalid, Fraz Munir Khan, Syed Abbas Ali, Zahid Hussain, Nadeem Bhattee
    TLDR Treatment strategies for breast cancer affect blood health, causing issues like anemia and require nutritional counseling.
    This retrospective study at the Bahawalpur Institute of Nuclear and Oncology in Pakistan involved 180 breast cancer patients and examined the impact of hormone receptor status on blood chemistry. The majority of patients were aged 41 to 60, with 57% at Stage III and 63.97% being post-menopausal. Half of the patients were ER/PR positive, and 23% had a triple positive status. Treatment varied based on hormone receptor status, with chemotherapy for hormone-negative patients, hormone therapy for hormone-responsive tumors, and monoclonal antibody therapy for Her-2 positive patients. The study found that treatment strategies affected hemogram values, leading to conditions like anemia, neutropenia, and nephrotoxicity. Adverse drug reactions included pain, fever, vomiting, hair loss, and lethargy. Nutritional counseling was recommended to improve patients' quality of life.
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