28 citations
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October 1985 in “The Journal of Cell Biology” This study identified two types of hard alpha-keratin filament assemblies in developing human hair follicles, which may help investigate the structural framework of mammalian keratin appendages.
January 2023 in “Indian Dermatology Online Journal” This article reviews the indications for micropigmentation in dermatological conditions like stable vitiligo and alopecia, but presents no new clinical results.
47 citations
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July 1998 in “Journal of Investigative Dermatology” A new mutation, Glu402Lys, in hair keratin is linked to variable symptoms of monilethrix.
21 citations
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November 2011 in “Veterinary Pathology” This study evaluated skin and hair color variations in different mouse strains, highlighting the association between hair cycle stages and skin pigmentation to better understand these features and their implications.
1 citations
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November 2022 in “Animals” This study found that differences in skin transcriptomes between juvenile and adult mink, as well as between black and white mink, suggest genes regulating hair color are active during early development rather than adulthood.
21 citations
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June 2004 in “Experimental Dermatology” This study found that Ber-EP4 immunoreactivity is present in specific areas of hair follicles across different stages of the hair cycle, particularly in the secondary hair germ, but not in mature anagen follicles.
2 citations
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September 2022 In this study, researchers found that a PER3 gene SNP may be pathogenic for a new subtype of dyschromatosis universalis hereditaria, especially when combined with a SASH1 mutation.
17 citations
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October 2011 in “International Journal of Immunopathology and Pharmacology” This study found that after 24 weeks of DPCP treatment for alopecia areata, there was a significant increase in new capillaries and hair regrowth detectable by videocapillaroscopy.
43 citations
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February 2008 in “Journal of cutaneous pathology” This study revealed that during fetal development, MITF and Mart-1 expressing melanocytes progress from the dermis to the epidermis and hair follicles, with MITF possibly marking follicular stem cells.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” In this study, researchers observed distinct morphological differences in hair follicles of mutant mouse genotypes, influenced by the expression levels of keratin2-6g, which is essential for proper hair follicle development.
11 citations
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April 2013 in “SpringerPlus” This study reports that melanocytes form a defined photoresponsive network in the skin that reads environmental light cycles and may influence the sleep-waking cycle similar to the pineal gland.
January 2019 in “Global Dermatology” This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.
21 citations
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April 2000 in “Journal of Cutaneous Pathology” This case report describes a 22-year-old woman with a nevoid plaque termed localized follicular hamartoma, characterized by skin-colored papules and specific cellular and structural features.
88 citations
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March 2004 in “Journal of Investigative Dermatology”
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Sox2 and BMP signaling may be key regulators of pigmentation and melanocyte migration, as suggested by experiments in mice, human biopsies, and cell co-cultures.
65 citations
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July 1984 in “Journal of Investigative Dermatology” 2 citations
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January 2010 This study observed that different hair types on Tianzhu white yaks have similar ultrastructures, but coarse hair fibers show distinct structural differences across body parts.
January 2024 in “Dermatology practical & conceptual” In this study, researchers found that the peripilar sign in patients with androgenetic alopecia does not indicate perifollicular infiltrate but is more frequent in individuals with lighter skin types due to contrast with the skin.
17 citations
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May 1969 in “American Journal of Physical Anthropology” This study describes unique anatomical characteristics of the skin and hair structures in the silver marmoset, including features such as thin epidermis, specialized nerve end-organs, and distinctive gland compositions.
September 2016 in “Journal of Dermatological Science” This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.
31 citations
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February 1999 in “Dermatologic surgery” This report describes a case where solar-induced postinflammatory hyperpigmentation following laser hair removal was treated with a combination of topical treatments and serial TCA peels, resulting in only slight improvement.
36 citations
,
February 1998 in “Journal of Anatomy” This study used fibre optic confocal imaging to visualize subsurface structures in live mouse skin, revealing cellular details and blood vessel networks that dynamic events could be studied in vivo.
1 citations
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January 2007 in “AIP conference proceedings” This study used phase contrast hard x-ray microscopy to capture detailed images of healthy human hair, revealing distinct structures such as the medulla, cortex, and cuticular layer.
19 citations
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November 2016 in “Developmental Biology” 29 citations
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July 2003 in “Experimental Dermatology” This study found that in anagen hair follicles, the basement membrane zone components showed decreased expression in the lower hair bulb, with a complete absence of BP230 at the dermal papilla junction, suggesting an incomplete hemidesmosome structure in these regions.
5 citations
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January 2011 in “International Journal of Cosmetic Science” This study found that 1,2,3,4-tetrahydroquinoline derivatives, particularly N-methyl-7-amino-1,2,3,4-tetrahydroquinoline, may be excellent blue dye candidates for human hair, offering superior color purity, stability, and fastness compared to 2,3-dihydroindoles.
33 citations
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October 2012 in “Journal of Morphology” This study identified the distribution of keratin-associated proteins during cornification in the epidermis of reptiles, revealing unique structural characteristics in sauropsid keratin proteins compared to other vertebrates.
66 citations
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June 2004 in “Biophysical Journal” Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
12 citations
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August 2001 in “PubMed” This study found that contrast enhanced phototrichogram (CE-PTG) significantly improved detection of various hair types and growth stages in androgenetic alopecia compared to standard PTG and was comparable to biopsy analysis.
31 citations
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February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.