Search

everythinglearnresearchcommunity

for

Search:↓

New genes and pathways are important for testosterone production and male sexual development.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Prolactin slows down hair growth in mice.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Some alternative treatments for hair loss might work, but more research is needed.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.