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    Glossary Histone Methylation

    process adding methyl groups to histone proteins, affecting gene expression

    Histone methylation is a biological process where methyl groups are added to histone proteins, which help package DNA in cells. This modification can either activate or repress gene expression, influencing how genes are turned on or off. For professionals, it's a key epigenetic mechanism that affects chromatin structure and function, playing a crucial role in development, differentiation, and disease.

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    1. Non-histone Methylation of SET7/9 and its Biological Functions Recent patents on anti-cancer drug discovery · 2021 · 3 citations
    2. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Genes & Development · 2008 · 667 citations
    3. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation PLoS ONE · 2007 · 98 citations
    4. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    5. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    6. Transcriptional regulation of the thymus master regulator <i>Foxn1</i> Science immunology · 2022 · 6 citations
    7. Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells Cell stem cell · 2011 · 5 citations
    8. Intracellular protons accelerate aging and switch on aging hallmarks in mice Journal of cellular biochemistry · 2018 · 4 citations
    9. Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases 2017 · 2 citations
    10. Trazodone by epigenetic mechanism can reverse the post finasteride syndrome Magna Scientia Advanced Research and Reviews · 2023
    11. 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro Journal of Investigative Dermatology · 2017
    12. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    13. Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata British Journal of Dermatology · 2011 · 48 citations
    14. Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory Advanced Healthcare Materials · 2017 · 22 citations
    15. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    16. Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration PLoS Genetics · 2021 · 6 citations
    17. Pediatric Endocrine-Disrupting Chemical Exposure Produces Irreversible Organizational Injury: Biomarker Evidence Necessitating a Precautionary Public Health Framework Scholarly review . · 2026
    18. Epigenetic Mechanisms, Assessment and Therapeutics of Epidermal Stem Cells in Skin Aging Stem Cells International · 2025
    19. Dynamics and Epigenetics of the Epidermal Differentiation Complex Epigenomes · 2024
    20. Epigenetic and Environmental Regulation of Skin Appendage Regeneration 2015
    21. Tailored chromatin modulation to promote tissue regeneration Seminars in Cell & Developmental Biology · 2019 · 10 citations
    22. Epigenetics and Other Autoimmune Skin Diseases Elsevier eBooks · 2015 · 2 citations
    23. The role of epigenetics in the pathogenesis of cutaneous diseases: a comprehensive review International Journal of Research in Medical Sciences · 2026
    24. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
    25. The Role of Histone Demethylases in Disease Springer eBooks · 2011 · 1 citations
    26. Is There a Histone Code for Cellular Quiescence? Frontiers in Cell and Developmental Biology · 2021 · 27 citations
    27. Epigenetics of Colorectal Cancer Gastroenterology · 2012 · 218 citations
    28. Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury Clinical Epigenetics · 2024 · 13 citations
    29. Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology · 2021 · 36 citations
    30. Noval advance of histone modification in inflammatory skin diseases and related treatment methods Frontiers in immunology · 2024