27 citations
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September 2015 in “PharmaNutrition” This article discusses various potential health benefits and increasing global interest in astaxanthin but presents no new clinical results, though ongoing trials are exploring its effects on chronic diseases and other conditions.
6 citations
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July 2013 in “Acta Clinica Belgica” This review discusses idiopathic hirsutism and suggests that combination treatment, including androgen suppression and cosmetic methods, is most effective, but notes that its pathogenesis remains unclear.
November 2025 in “The Journal of Sexual Medicine” This study found that the Mark Cuban Cost Plus Drug Company model offers substantial cost savings on men's health medications compared to Medicare and GoodRx, particularly for long-term treatments.
March 1997 in “The Lancet” Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
15 citations
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July 2021 in “AAPS PharmSciTech” January 2005 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” This article examines how the Dietary Supplement Health and Education Act of 1994 allows ineffective herbal remedies for hair loss to remain on the market, potentially misleading consumers, and suggests possible solutions.
3 citations
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February 2023 in “Journal of Experimental Pharmacology” This study found that LHE may prevent and reverse testosterone-induced prostatic hyperplasia, supporting the traditional use of Kigelia africana for some reproductive system disorders.
24 citations
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March 2002 in “Expert opinion on investigational drugs” This review discusses various anti-androgen treatments for hirsutism, including androgen receptor blockers and inhibitors, and emphasizes the role of diagnosis in selecting the most appropriate therapy, but reports no new clinical results.
December 2024 in “Quality in Sport” This review found that hormones significantly impact women's health and athletic performance, influencing the menstrual cycle, menopause, and exercise responses, while therapies like contraception and hormone replacement require personalized approaches to balance benefits and risks.
December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)” This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).
April 2025 in “Journal of Reproductive Healthcare and Medicine” This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.
April 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study developed and tested a herbal hair growth tonic using medicinal plant extracts on animal models, reporting higher anagen/telogen ratio, follicular density, and hair length compared to controls, suggesting it as a potential natural alternative to synthetic products.
11 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review explores the evaluation and treatment of hirsutism, emphasizing a systematic approach to uncovering its causes and recommending combination therapies for effective management, but presents no new results.
April 2026 in “The Journal of Urology” This study found that men taking 1 mg/day of finasteride had significantly reduced sperm production and morphology but similar hormonal, sexual, and psychological profiles compared to controls, suggesting finasteride affects semen quality without altering other physiological functions.
24 citations
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September 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This article discusses the combination of mechanical hair removal and medication use for hirsutism improvement, noting that no drugs are approved for this condition in North America, and calls for well-designed comparative studies.
June 2023 in “Journal of Natural Remedies” This study found that the methanolic extract of Hibiscus rosa sinensis exhibits promising 5α-reductase inhibitory activity, suggesting its potential use in the treatment of androgenic conditions like male pattern hair loss and benign prostatic hyperplasia.
December 2025 in “Seven Editora eBooks” This integrative review found that while hormone therapy, under proper medical supervision, can improve quality of life by treating conditions like muscle and bone mass loss, using these hormones without clinical need poses serious risks to neurological, cardiac, hepatic, renal, and reproductive health.
3 citations
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January 2017 in “Journal of cosmetology & trichology” This study reports that a nutritional complex may improve hair density and quality, with in vitro findings demonstrating inhibition of 5α-reductase, and participants noting reduced hair loss and greasiness.
January 2025 in “International Journal of Dermatology Research” In this study, a herbal preparation inhibited the conversion of testosterone to DHT and its binding on hair roots in vitro, suggesting potential as an alternative treatment for androgenic alopecia without the safety concerns associated with finasteride.
15 citations
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December 2021 in “Pharmaceutics” This systematic review identified robust biomarkers associated with hidradenitis suppurativa and confirmed potential drugs for repurposing, highlighting key pathogenetic pathways and their links to comorbid disorders.
This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.
2 citations
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January 2020 Certain dietary supplements can improve hair health.
23 citations
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October 2015 in “Andrology” This review discusses the physiological basis, history, and current development of male hormonal contraception, highlighting its potential risks and benefits, but reports no new research findings.
2 citations
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August 2013 in “International Journal of Herbal Medicine” This review discusses the historical concepts of hirsutism in Unani Medicine and evaluates herbal treatments, indicating these may influence underlying endocrine issues but current evidence remains insufficient.
April 2026 in “Journal of Cosmetic Dermatology” This systematic review found that oral nutraceuticals significantly improved various measures of hair growth compared to placebo, but concluded that more rigorous research is needed to confirm these findings.
3 citations
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December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
This article discusses solitary hirsutism, emphasizing that treatment is mostly cosmetic unless contraception is also desired, and reports no new clinical results.
August 2025 in “http://isrctn.com/” The supplement may improve hair growth and skin health with some mild risks.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review examined a polyherbal hair formulation aimed at managing male pattern baldness, reporting that its ingredients may enhance scalp blood circulation, strengthen hair follicles, and promote hair regrowth through various mechanisms such as antioxidant and DHT-inhibiting effects.
October 2025 in “Dermatology and Therapy” This study observed that adults with thinning hair who ingested a patented botanical-based supplement experienced significant increases in hair shaft diameter and reductions in hair breakage over 180 days, suggesting improved hair strength and length across various demographic groups.