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research Improved Humidity-Resistant Hair Straightening Using a Cysteamine-Derived Amino Acid Compound
In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
research 1323 Human dermal fibroblasts and mast cell populations are altered in hidradenitis suppurativa, with epithelial-mesenchymal-transition signals ameliorated by spleen tyrosine kinase antagonism.
This study demonstrates that human epidermal stem cells can adapt to environmental temperature changes through mTOR signaling, and prolonged inhibition of mTORC1 supports stem cell maintenance, which may be vital for regenerative medicine.
research Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism
This study observed that partial autotaxin deficiency in mice protects against diet-induced obesity and systemic insulin resistance, suggesting the ATX-LPA pathway negatively affects skeletal muscle insulin signaling and mitochondrial function during obesity.
research Dihydrotestosterone induces arterial stiffening in female mice
This animal study observed that dihydrotestosterone increased arterial stiffness and decreased estrogen receptor expression in female mice, potentially impacting cardiovascular health in contexts of androgen use.
research Follicular Isolation Technique with De-Epithelialization for Eyebrow and Eyelash Reconstruction
This study found that combining follicular isolation with de-epithelialization in eyebrow and eyelash transplantation led to better outcomes and fewer complications than using follicular isolation alone.
research Hirsutism
This article reviews the physiology, causes, and treatments of hirsutism and reports no new research findings.
research H2AK119ub dynamics control hair follicle stem cell quiescence
This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.
research Hypoxia inducible factor-1α promotes trichogenic gene expression in human dermal papilla cells
This study found that HIF-1α suppression in dermal papilla cells of androgenetic alopecia patients reduces the expression of trichogenic genes, suggesting it as a potential target for hair loss treatment.
research How I Do It: The “Sweet Spot” for Strip Harvesting
This article invites ISHRS members to contribute insights to the "How I Do It" section, emphasizing shared clinician experiences as vital to advancing standards in hair loss treatment, but it reports no research findings.
research A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia
This study identifies a mutation in the hairless gene that may impact thyroid receptor interaction, contributing to alopecia universalis congenita in an Arab Israeli patient.
research Epithelial differentiation of human adipose-derived stem cells (hASCs) undergoing three-dimensional (3D) cultivation with collagen sponge scaffold (CSS) via an indirect co-culture strategy
This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.
research Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair
This study suggests that the mechanical robustness of hair may be enhanced by the binding interactions of keratin-associated proteins, particularly KAP8.1, with intermediate filament proteins.
research Tissue Harvesting | HuBMAP | JHU-TMC v1
Quickly fix tissue in formalin after excision to preserve it.
research Clinical and endocrine effects of finasteride, a 5α-reductase inhibitor, in women with idiopathic hirsutism
In this study, women with idiopathic hirsutism who took finasteride for 9 months experienced a significant reduction in hirsutism scores compared to those receiving a placebo, with minimal side effects.
research Cyproterone acetate for hirsutism
This review found that adding cyproterone acetate to estradiol showed a subjective improvement in hirsutism versus placebo, but comparisons with other therapies revealed no clinical differences.
research Visually scoring hirsutism
This review examines various methods for assessing hair growth in women, highlighting the usefulness of the mFG visual scoring method for diagnosing hirsutism despite its limitations.
research Hair standing on end as a manifestation of iron deficiency?
research Muscular Increase and Definition of the Back Contour Through Key Fat Grafting and Liposuction
This study investigated a fat grafting technique (MID BACK) to enhance back muscle definition in patients undergoing liposculpture, reporting no adverse events and only minor complications, suggesting the method is safe and effective for improving muscular contours and correcting spinal asymmetries.
research Hair mass index obtained by cross-section trichometry: an objective and clinically useful parameter to quantify hair in chemotherapy-induced alopecia
In this study, cross-section trichometry was found to be a precise method for measuring hair loss in chemotherapy patients, but marking the measurement site on the scalp is not always necessary.
research Advanced Lipotransfer Techniques
This article describes a procedure involving skin marking, tumescent anesthesia, and micrograft mobilization, but does not present any study findings or results.
research Myotonic dystrophy type 1
In this thesis, researchers explored ways to enhance the management of myotonic dystrophy type 1 by investigating the genetic inheritance patterns, especially small-sized repeat expansions, and assessing cardiac care, energy expenditure, and body composition in affected individuals.
research Successful Treatment of Hirsutism in HAIR-AN Syndrome Using Flutamide, Spironolactone, and Birth Control Therapy
This case report describes the treatment of hirsutism in a 15-year-old obese Mexican girl with flutamide, aiming to improve her social function.
research Testosterone+Finasteride Improves Body Composition After Spinal Cord Injury: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
This pilot study suggests that high-dose testosterone plus finasteride improved body composition in men with impaired gait and low to low-normal testosterone after chronic incomplete spinal cord injury.
research Hypoxic Preconditioned Nanofat at 1% O2 for 24 h Loses Its Regenerative In Vivo Vascularization Capacity
This study found that hypoxic preconditioning of nanofat from donor mice reduced its vascularization capacity in vivo, suggesting that this approach cannot currently enhance nanofat's regenerative potential.
research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism
This study found that the combination of spironolactone and finasteride significantly improved hirsutism scores more than spironolactone alone in women, with similar side-effect profiles between treatments.
research Le gènehairlessde la souris
This study suggests that the hairless gene encodes a nuclear factor important for hair follicle integrity, and its absence leads to hair follicle loss and defects in tissue development.
research Individualized homoeopathic treatment in subclinical hypothyroidism: A case report
In this report, a 47-year-old woman with subclinical hypothyroidism experienced significant symptom relief and normalized TSH levels after six months of individualized homeopathic treatment with Sepia 1M, targeted to her symptom profile.
research Clinical profile of 50 premenopausal women with hirsutism
This study found that among women with hirsutism, acne was the most common associated feature, and severity varied with related conditions like menstrual irregularities and obesity.
research Where are we in the diagnosis and treatment of hirsutism? A narrative review
In this review, the authors provide an updated overview of hirsutism, highlighting new insights into androgen action, assessment methods, and treatment options, aiming for a personalized approach to manage this complex endocrine and psychological condition.