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Did you mean Steroid Pulse Therapy?

Glossary Steroid Pulse Therapy

involves administering high doses of corticosteroids briefly to reduce severe inflammation

Steroid Pulse Therapy, also known as Pulse Steroid Therapy or High-Dose Steroid Therapy, involves administering high doses of corticosteroids over a short period, typically to manage severe inflammation or autoimmune conditions. This approach aims to quickly reduce symptoms and control disease activity, often followed by a tapering schedule to minimize side effects.

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research High-dose steroid pulse therapy for the treatment of severe alopecia areata.

21 citations , March 2002 in “PubMed”

This study found that monthly high-dose steroid pulse therapy for approximately six months was effective and well-tolerated in Taiwanese patients with severe multifocal alopecia areata.

research Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata: A Retrospective Study

19 citations , January 2013 in “Annals of Dermatology”

In this study, oral steroid pulse therapy was found to be as effective and well-tolerated as intravenous pulse therapy in treating severe alopecia areata, especially when started within one year of disease onset.

research Interest of High-Dose Pulse Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata: A Retrospective Case Series

39 citations , January 2012 in “Dermatology”

In this study, the combination of pulse intravenous corticosteroids and methotrexate was associated with positive hair regrowth in severe alopecia areata patients, with half achieving total regrowth.

research Comparison of High-Dose Corticosteroid Pulse Therapy and Combination Therapy Using Oral Cyclosporine with Low-Dose Corticosteroid in Severe Alopecia Areata

14 citations , January 2015 in “Annals of dermatology/Annals of Dermatology”

This study found that corticosteroid pulse therapy may be more effective than oral cyclosporine with corticosteroid for patients with severe alopecia areata, especially for those with the plurifocal type or a short disease duration.

research Steroid topical therapy and pulse dosing therapy for multifocal alopecia areata

January 2003 in “Journal of Practical Aesthetic and Plastic Surgery”

This study found that intralesional Diprospan injections and high-dose intravenous methylprednisolone may be effective for treating longstanding multifocal alopecia areata, with variable hair regrowth observed among patients.

research [A case of "syndrome of progressive muscle spasm, alopecia, and diarrhea (Satoyoshi)" treated with steroid pulse therapy].

16 citations , June 1992 in “PubMed”

In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.

research Sequential high‐ and low‐dose systemic corticosteroid therapy for severe childhood alopecia areata

18 citations , January 2017 in “Journal der Deutschen Dermatologischen Gesellschaft”

This study reports that sequential high- and low-dose prednisolone therapy effectively promotes complete hair regrowth in 62% of children with severe alopecia areata, while minimizing severe side effects.

research Prognostic factors in methylprednisolone pulse therapy for alopecia areata

27 citations , May 2011 in “Journal of dermatology”

In this study, methylprednisolone pulse therapy was found to be effective for severe alopecia areata patients, especially those with a short disease duration or plurifocal type.

research Back to the Basics: Response of Alopecia Areata Universalis to Intravenous High-Dose Pulse Corticosteroid Therapy

October 2021 in “Dermatology practical & conceptual”

High-dose corticosteroids can significantly regrow hair in severe alopecia areata.

research Limited Effectiveness of Platelet-Rich-Plasma Treatment on Chronic Severe Alopecia Areata

1 citations , January 2014 in “Hair therapy & transplantation”

This review discusses various treatment options for Alopecia Areata, focusing on both medical and psychological approaches, and reports no new clinical results.

research Clinical Profile and Outcomes of Filipino Lupus Patients with Myocarditis in a Tertiary Hospital

September 2019 in “Philippine Journal of Internal Medicine”

This study found that Filipino patients with lupus typically develop myocarditis early and respond well to early immunosuppressive therapy.

research Alopecia Areata: An Update on Treatment Options for Children

21 citations , May 2017 in “Paediatric drugs”

Individualized treatment plans are crucial for children with alopecia areata, with promising options like JAK inhibitors showing significant hair regrowth.

research Advances in the management of alopecia areata

51 citations , December 2011 in “The Journal of Dermatology”

This review discusses updated treatment guidelines for alopecia areata in Japan, highlighting new options like corticosteroid pulse therapy, but reports no new clinical results.

Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse Therapy

research Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse (DCP) Therapy

20 citations , October 2003 in “The Journal of Dermatology”

This study observed that while dexamethasone-cyclophosphamide pulse therapy is relatively free from hypertension and diabetes compared to conventional steroids in pemphigus patients, it frequently causes generalized weakness and flushing.

research Therapies

August 2010 in “The Journal of Dermatology”

The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.

research Adult Onset Still Disease

May 2021 in “Medicina internă”

This case report highlights a 31-year-old male with Adult Onset Still Disease, whose symptoms, including high fever, responded only to pulse-therapy with Methylprednisolone after failing to improve with usual treatments.

research [Successful treatment of "steroid-immunosuppressant resistant" polymyositis with immunoadsorption].

1 citations , November 1991 in “PubMed”

This report describes a case of polymyositis that was resistant to steroids and immunosuppressants but showed improvement with immunoadsorption therapy.

Comparative Efficacy and Adverse Clinical Events of Methotrexate Versus Azathioprine with Steroid Mini Pulse Therapy in the Management of Moderate to Severe Alopecia Areata: A Tertiary Centre Based Interventional Study

research Comparative Efficacy and Adverse Clinical Events of Methotrexate versus Azathioprine with Steroid Mini Pulse Therapy in the Management of Moderate to Severe Alopecia Areata: A Tertiary Centre Based Interventional Study

March 2022 in “Nepal Journal of Dermatology Venereology & Leprology”

In this prospective clinical trial, azathioprine with steroid minipulse therapy and methotrexate with steroid minipulse therapy both improved hair regrowth in alopecia areata patients, but methotrexate showed slightly higher efficacy.

research Recalcitrant widespread alopecia areata in a child treated successfully with oral methylprednisolone pulse therapy

July 2013 in “Our Dermatology Online”

In this case study, an 11-year-old boy with extensive alopecia areata showed 80% hair regrowth after six months of treatment with methylprednisolone despite initial lack of response to topical therapies.

research Medium-dose prednisolone pulse therapy in alopecia areata

17 citations , November 2009 in “Dermato-endocrinology”

This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.

research A systematic review of pulse steroid therapy for alopecia areata

50 citations , January 2016 in “Journal of the American Academy of Dermatology”

This systematic review of pulse corticosteroid therapy for alopecia areata found relatively low complete response rates, but responders experienced low relapse rates, indicating potential benefits for patients with favorable prognostic factors.

Alemtuzumab-Induced Secondary Autoimmune Skin Disorders as Side Effects of Multiple Sclerosis Therapy: Problem That Can Be Influenced or Fate? A Narrative Overview of the Literature and a Neuroprotective Role of Vitamin D

research Alemtuzumab-Induced Secondary Autoimmune Skin Disorders as Side Effects of Multiple Sclerosis Therapy: Problem That Can Be Influenced or Fate? A Narrative Overview of The Literature A Neuroprotective Role of Vitamin D?

January 2022 in “Medical research archives”

This article reviews the potential role of vitamin D supplementation as an adjunct to alemtuzumab therapy in multiple sclerosis management, noting its possible benefits for autoimmune comorbidities and patient adherence, but reports no new clinical results.

Unilateral Thalamic Infarction Associated With Rupture of Dissecting Posterior Cerebral Artery in Childhood-Onset Systemic Lupus Erythematosus: A Case Report

research Unilateral Thalamic Infarction Associated with Rupture of Dissecting Posterior Cerebral Artery in Childhood-Onset Systemic Lupus Erythematosus: A Case Report

November 2021 in “Research Square (Research Square)”

This case report describes the first recorded instance of posterior cerebral artery dissection in a patient with childhood-onset systemic lupus erythematosus, which uniquely progressed from cerebral infarction to subarachnoid hemorrhage.

research Intravenous methylprednisolone pulse therapy in severe alopecia areata

14 citations , January 2015 in “Indian journal of dermatology, venereology, and leprology”

This study found that methylprednisolone pulse therapy may be an effective treatment option for patients with severe multifocal alopecia areata, particularly those experiencing their first episode.

research Targets to treat androgen excess in polycystic ovary syndrome

14 citations , September 2015 in “Expert Opinion on Therapeutic Targets”

This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.

research Alopecia Areata and Alopecia Areata Incognita

1 citations , July 2018 in “Elsevier eBooks”

This research focuses on alopecia areata, highlighting the psychological impact, especially of its variant alopecia areata incognita, and provides diagnostic and treatment tips, but does not report specific results.

research Alopecia areata. Diagnostic and therapeutic recommendations of the Polish Society of Dermatology. Part 2: Treatment

1 citations , January 2023 in “Przegląd Dermatologiczny”

This review discusses current and emerging treatments for alopecia areata, emphasizing systemic treatments for moderate to severe cases, and reports no new clinical results.

research 008 Stratifying alopecia areata systemic treatments: Tailored approaches to disease severity

July 2024 in “Journal of Investigative Dermatology”

Tailored treatments for alopecia areata show promising results, with pulse steroids effective for mild cases and Ritlecitinib, Dupilumab, or methotrexate and prednisone effective for severe cases.

research Weekly azathioprine pulse versus betamethasone oral mini-pulse in the treatment of moderate-to-severe alopecia areata

10 citations , July 2019 in “Indian Journal of Dermatology”

This study found that azathioprine pulse therapy and betamethasone both effectively managed alopecia areata with similar hair regrowth results, though betamethasone had significantly more side effects, suggesting azathioprine as a preferable alternative to corticosteroids.

Alopecia Areata: An Autoimmune Hair Loss Condition

research Alopecia Areata

January 2016 in “Springer eBooks”

This review examines the clinical presentation and management strategies for alopecia areata, focusing on pediatric patients, and highlights the need for addressing its psychological impacts; it reports no new clinical findings.