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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Androgens can both increase and decrease hair growth in different parts of the body.

PGD2 stops hair growth and is higher in bald men with AGA.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Targeted cancer therapies often cause serious skin problems that need careful management.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Researchers created human hair follicles using a new method that could help treat hair loss.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Special fiber materials boost the healing properties of certain stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.