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Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Fat cells in the skin help start healing and form important repair cells after injury.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Hair follicle regeneration needs special conditions and young cells.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.