48 citations
,
April 2015 in “PLOS ONE” In this study, hirsutism was found to have the most significant negative impact on health-related quality of life among Iranian women with polycystic ovary syndrome.
10 citations
,
November 2008 in “Veterinary Dermatology” In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.
30 citations
,
December 2021 in “Frontiers in Microbiology” In this study, researchers found that cepharanthine significantly inhibited HSV-1 replication in vitro by interfering with specific signaling pathways, arresting the cell cycle, and inducing apoptosis in infected cells, highlighting its potential as an antiviral agent.
1 citations
,
May 2011 in “Molecular Medicine Reports” This study found no association between the -866G/A polymorphism in the UCP2 gene and the development of polycystic ovary syndrome.
1 citations
,
January 2006 This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.
52 citations
,
November 2003 in “Journal of Investigative Dermatology” In this study, mutations in the CDH3 gene were identified as the cause of hypotrichosis with juvenile macular dystrophy, and the researchers observed substantial phenotypic variability among affected individuals.
47 citations
,
March 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study identified 43 compounds in Platycladi Cacumen, including flavonoids, and found significant chemical variation in flavonoid content across different regions and processed products.
March 2011 in “Open Archive (Karolinska Institutet)” This study explored the effects of a common Hutchinson-Gilford progeria syndrome mutation in an inducible mouse model, revealing skin abnormalities similar to those in affected patients.
3 citations
,
January 2022 in “Burns & Trauma” This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
14 citations
,
August 2020 in “Journal of cosmetic dermatology” This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.
6 citations
,
December 2011 in “Clinical and Experimental Dermatology” A woman developed rare, unexplained curly hair on her scalp and eyelashes.
April 2014 in “The FASEB Journal” This study found that maternal hephaestin knockout in mice leads to neonatal hair loss, likely due to low iron levels in the mother's milk.
November 2011 in “Hair transplant forum international” This article provides an update from the ISHRS Practice Census Subcommittee and Media Relations Committee for 2011 but presents no new research results.
13 citations
,
March 2019 in “Medicina Clínica (english Edition)” This paper reviews the complexities of diagnosing and managing polycystic ovary syndrome, emphasizing the importance of individualized treatment to address symptoms due to hyperandrogenism, ovarian dysfunction, and metabolic issues, but reports no new results.
2 citations
,
January 1984 in “PubMed” This study concluded that cimetidine did not significantly affect hair growth in women with hirsutism, despite a notable decrease in urine 17-ketosteroids.
January 2019 in “Publisher” This study found that human basal cell and squamous cell carcinomas have distinct gene expression patterns, with specific up-regulation of zinc finger encoding genes in basal cell carcinoma.
December 2025 in “BENTHAM SCIENCE PUBLISHERS eBooks” This chapter reviews the clinical presentation of Polycystic Ovary Syndrome and its differentiation from other conditions, but reports no new clinical results.
June 2024 in “British Journal of Dermatology” This narrative focuses on the experiences of two women with permanent chemotherapy-induced alopecia, highlighting the severe psychological and social impact along with dissatisfaction over pre-treatment information about hair loss, which they initially believed to be temporary.
2 citations
,
March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study strongly suggests that a distinct form of hereditary localized alopecia in a Chinese family is linked to a novel locus on chromosome 2p25.1–2p23.2.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” This case report describes a 46,XY female patient with a novel homozygous nonsense mutation in the LHCGR gene, highlighting the need for molecular analysis in disorders of sexual development.
January 2023 in “Skin appendage disorders” This article describes two cases of plica neuropathica, a rare hair condition involving severe matting, and discusses possible contributing factors and diagnosis methods while reporting no new scientific results.
December 2004 in “Annales d Urologie” This article examines the PCPT study on whether daily finasteride can reduce prostate cancer incidence, describing its methodology and findings but reporting no new clinical results.
April 2025 in “International Journal of Homoeopathic Sciences” This case report describes marked improvement in symptoms for a 24-year-old woman with PCOS following individualized homeopathic treatment, which reportedly included a reduction in irregular menstruation, vaginal discomfort, and weight gain.
37 citations
,
January 2008 in “Gynecological Endocrinology” This study found that in women with polycystic ovary syndrome, shorter CAG repeat lengths in the androgen receptor gene were associated with lower dihydrotestosterone and androstenedione levels, but a higher prevalence of acne and hirsutism.
2 citations
,
April 2021 in “JAAD International” This article discusses the potential safety of platelet-rich plasma therapy for cicatricial alopecia but highlights that its effectiveness is still uncertain; no new empirical results are provided.
85 citations
,
January 2014 in “Hormone Research in Paediatrics” This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.
4 citations
,
December 2021 in “Journal of clinical laboratory analysis” This study identified a splicing-site deletion in the DCAF17 gene associated with Woodhouse-Sakati syndrome in a large consanguineous pedigree, leading to typical phenotypic features.
51 citations
,
November 2011 in “Reproductive Biology and Endocrinology” In this study of reproductive-aged women in Tehran, idiopathic hirsutism and polycystic ovary syndrome were reported to be prevalent, with rates influenced by the screening methods used.
41 citations
,
November 2019 in “Journal of Ultrasound in Medicine” This study found that 70-MHz ultrasound can detect early signs of hidradenitis suppurativa linked to severity, including hair follicle abnormalities and keratin fragmentation, aiding in diagnosis and management.
September 2025 in “PubMed” In this Delphi study, international experts established consensus-based guidelines for diagnosing and managing persistent chemotherapy-induced alopecia (pCIA), recommending prevention through scalp cooling and early use of minoxidil, while advising against bicalutamide and certain finasterides for breast cancer patients due to safety concerns.