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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Fungi-produced compounds can change plant root growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Aging causes skin stem cells to work less effectively.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Wnt signaling is crucial for skin development and hair growth.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.