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    Glossary Hair Follicle Pigmentation

    process of melanin deposition in hair shaft

    Hair follicle pigmentation refers to the process by which melanin, the natural pigment produced by specialized cells called melanocytes, is deposited in the hair shaft within the hair follicle. This pigmentation determines the color of the hair, ranging from black and brown to blonde and red, and can be influenced by genetic factors, hormonal changes, and aging.

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    1. Hair Follicle Pigmentation 2005 · 450 citations
    2. The cell biology of human hair follicle pigmentation Pigment cell & melanoma research · 2010 · 127 citations
    3. Aging of the hair follicle pigmentation system International journal of trichology · 2009 · 75 citations
    4. Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro PLOS ONE · 2019 · 6 citations
    5. Exosomal miR ‐199a‐3p From Dermal Papilla Cells Regulates Hair Follicle Pigmentation by Targeting POU2F1 in Melanocytes The FASEB Journal · 2026
    6. 1363 Hair follicle growth and pigmentation during ageing Journal of Investigative Dermatology · 2018
    7. Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation Pigment Cell & Melanoma Research · 2011 · 240 citations
    8. Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis 2013 · 29 citations
    9. mTORC1 activity negatively regulates human hair follicle growth and pigmentation EMBO reports · 2023 · 12 citations
    10. Sox2 in the dermal papilla regulates hair follicle pigmentation Cell reports · 2022 · 9 citations
    11. Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo Archives of Dermatological Research · 2021 · 7 citations
    12. Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models 2019 · 6 citations
    13. Hair Follicle Melanogenesis Reflected in Hair Pigmentation as a Developmental Factor in Alopecia Areata Skin appendage disorders · 2021 · 3 citations
    14. 1376 Dermal white adipose tissue enhances proliferation, pigmentation and hair shaft elongation in human hair follicles ex vivo Journal of Investigative Dermatology · 2018
    15. A neuroendocrinological perspective on human hair follicle pigmentation Pigment Cell & Melanoma Research · 2010 · 56 citations
    16. 602 mTORC1 activity controls human scalp hair follicle pigmentation and growth 2021 · 1 citations
    17. 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation 2016
    18. The effect of flavonoids on regenerated hair follicles with pigmentation Journal of Dermatological Science · 2017
    19. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    20. Vasoactive Intestinal Peptide Operates as a Negative Regulator of Human Hair Follicle Pigmentation Ex Vivo Journal of Investigative Dermatology · 2024
    21. 640 Exploring the synergic effects of a plant and a peptide on hair follicle pigmentation Journal of Investigative Dermatology · 2022
    22. A simple assay for the study of human hair follicle damage induced by ionizing irradiation Experimental dermatology · 2009 · 16 citations
    23. Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp Scientific reports · 2020 · 14 citations
    24. New frontiers in human hair follicle (neuro‐)endocrinology Experimental dermatology · 2006
    25. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    26. A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics Biology · 2023 · 20 citations
    27. The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle 2015 · 15 citations
    28. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations
    29. Dermal papilla regulation of hair growth and pigmentation Advances in stem cells and their niches · 2019 · 3 citations
    30. Effects of gamma rays on the regeneration of murine hair follicles in the natural hair cycle International Journal of Radiation Biology · 2017 · 3 citations