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    Glossary Hair Follicle Bulge Stem Cells

    specialized cells that regenerate hair and repair skin

    Hair Follicle Bulge Stem Cells are specialized cells located in a specific region of the hair follicle known as the "bulge." These cells have the unique ability to regenerate and produce new hair, as well as repair damaged skin. They play a crucial role in the hair growth cycle and are a key focus in research on hair loss treatments and skin regeneration therapies.

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    1. Autofluorescence in the Stem Cell Region of the Hair Follicle Bulge Journal of Investigative Dermatology · 2005 · 17 citations
    2. Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers Journal of Biomaterials Science Polymer Edition · 2020 · 11 citations
    3. Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development Frontiers in cell and developmental biology · 2020 · 10 citations
    4. Isolation of Mouse Hair Follicle Bulge Stem Cells and Their Functional Analysis in a Reconstitution Assay Methods in molecular biology · 2016 · 7 citations
    5. The Developmental & Molecular Requirements for Ensuring that Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation Cell transplantation · 2021 · 4 citations
    6. Two-layered electrospun nanofibrous mat loaded chitosan nanoparticles, growth factors and hair follicle bulge stem cells can promote wound healing in rat Regenerative Medicine · 2026
    7. 599 PPARg signaling modulation protects from hair follicle bulge stem cell damage and cyclophosphamide-induced hair follicle cytotoxicity 2019
    8. 621 An apple stem cell-derived extract increases epithelial stem cells number in the hair follicle bulge Journal of Investigative Dermatology · 2019
    9. Identification of Bulge Stem Cells in Mouse and Human Hair Follicles Microscopy research · 2018 · 4 citations
    10. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    11. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Proceedings of the National Academy of Sciences · 2005 · 419 citations
    12. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    13. Hair follicle bulge-derived stem cells promote tissue regeneration during skin expansion Biomedicine & Pharmacotherapy · 2020 · 27 citations
    14. Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury 2020 · 4 citations
    15. Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells Cancer Research · 2010
    16. Isolation, Cultivation, and Morphological Characteristics of Hair Follicle Adult Stem Cells in the Bulge Region in Mouse and Human Microscopy research · 2020 · 1 citations
    17. Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells Dermatology · 2007 · 16 citations
    18. The Hair Follicle Bulge: A Niche for Adult Stem Cells Microscopy and Microanalysis · 2011 · 19 citations
    19. 732 Treatment with cyclohexyl salicylate, an olfactory receptor 2A4/7 agonist, promotes human hair follicle growth and bulge stem cell progeny expansion Journal of Investigative Dermatology · 2022
    20. Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata 2010 · 20 citations
    21. Differential distribution of the epigenetic marker 5‐hydroxymethylcytosine occurs in hair follicle stem cells during bulge activation Journal of Cutaneous Pathology · 2019 · 4 citations
    22. In Vitro differentiation of hair-follicle bulge stem cells into synaptophysin-expressing neurons: a potential new approach for neuro-regeneration Human Cell · 2024
    23. In vitro identification of a stem cell population from canine hair follicle bulge region 2017 · 5 citations
    24. 1393 Lower proximal cup cells but not bulge stem cells regenerate hair follicles after chemotherapy injury Journal of Investigative Dermatology · 2018 · 1 citations
    25. Characterization and isolation of stem cell–enriched human hair follicle bulge cells ˜The œYear book of dermatology · 2007
    26. Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells Cellular reprogramming · 2014 · 3 citations
    27. Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells Veterinary Dermatology · 2009 · 37 citations
    28. Preliminary study on reconstruction of hair follicle by cell mass of dermal papilla cells and bulge stem cells Shiyong kouqiang yixue zazhi · 2011
    29. 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    30. ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022