December 2023 in “Journal of Asia Pacific Aesthetic Sciences” This study found that a novel method of isolating human follicle stem cells from hair follicles via mechanical centrifugation, without culture conditions, promises to improve hair density in patients with Androgenetic Alopecia and some cases of Alopecia Areata.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
December 1998 in “福井大学教育学部紀要 第4部 教育科学” This study found that the bioconjugate nanoparticle HA-P5 significantly alleviated acne and reduced sebum production by inhibiting key signaling pathways without inducing unwanted protein expression that hinders acne treatment.
1 citations
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January 1985 in “Protides of the biological fluids” This study found that injecting highly purified monocyto-angiotropin into hare skin induced new blood vessel formation and significantly accelerated hair growth at the injection site compared to control areas.
September 2017 in “Journal of Investigative Dermatology” This study found that after four weeks of daily use, the roughness of the hair surface significantly decreased, as shown through quantitative image analysis using HIROX.
98 citations
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June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
50 citations
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February 2004 in “Genomics” This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
30 citations
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January 2013 in “Human Mutation” This study identified a homozygous frameshift mutation in the HOXC13 gene associated with pure hair and nail ectodermal dysplasia in a consanguineous Syrian family, suggesting crucial roles for HOXC13 in hair and nail development.
January 2026 in “MDPI (MDPI AG)” This study revealed that heterozygous mice with the hairy ear mutation exhibited significant gene expression changes related to hair growth, such as upregulation of hair keratin and keratin-associated proteins, shedding light on the Hoxc gene cluster's role in this phenotype.
34 citations
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January 2016 in “Analytical Chemistry” This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.
4 citations
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May 2007 in “Journal of Dispersion Science and Technology” This study found that hinokitiol in cationic vesicles promoted hair growth in mice, potentially due to its high substantivity on the skin.
November 2025 in “Informatica” This study introduces a novel image enhancement method that significantly improves the visual quality of low-light sports images by utilizing improved bilateral filtering and the CLAHE algorithm, achieving a 65.24% improvement in color and edge detail preservation compared to state-of-the-art methods on the LOL dataset.
16 citations
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January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.
August 2022 in “JAAD case reports” This case report describes a 36-year-old woman with hidradenitis suppurativa whose condition progressed to rapidly fatal squamous cell carcinoma, highlighting the potential for aggressive tumor development linked to specific protein markers.
This study reported that the Fe@C/CB electrocatalyst effectively detected Metol in water samples with a low detection limit, high sensitivity, and good stability, suggesting it as a promising tool for environmental monitoring.
11 citations
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July 2010 in “European Journal of Dermatology” In this study, researchers confirmed linkage of a form of hair-nail ectodermal dysplasia to chromosome 12 in a Pakistani family, suggesting a possible non-coding mutation in KRTHB5 or a mutation in an unknown gene.
September 2026 in “Angewandte Chemie” In this research, SEU-302, a newly developed covalent organic framework, exhibited significant antibacterial and wound-healing properties in vitro and in vivo, effectively eliminating Staphylococcus aureus and reducing inflammation under light activation, thereby showcasing its potential for therapeutic photodynamic applications.
36 citations
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December 2009 in “Skin pharmacology and physiology” In this study, helium-neon laser irradiation at approximately 1 J/cm² significantly increased the percentage of hair follicles in the anagen phase in both testosterone-treated and untreated mice, suggesting stimulation of hair growth.
8 citations
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January 2016 in “Skin research and technology” This study found that a new 12-point scale provided a more precise measurement system for evaluating hair damage and improvement after hair care product use compared to a 5-point scale.
July 2025 in “Journal of Cosmetic and Laser Therapy” This case study reported rare alopecia resulting from a hyaluronic acid filler injection, noting approximately 80% hair regrowth after treatment with topical minoxidil.
7 citations
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May 2014 in “Iranian Red Crescent medical journal” This case study describes a 17-year-old female with severe hirsutism diagnosed with PCOS, NC-CAH, and HAIR-AN syndrome who was successfully treated based on her specific underlying conditions.
1 citations
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September 2024 in “Journal of Oncology Pharmacy Practice” In this report, a 77-year-old woman treated for essential thrombocytosis with low-dose hydroxyurea experienced an unexpected change in hair color from gray to dark brown after 20 weeks, highlighting a potential aesthetic side effect of the drug, in addition to therapeutic effects.
September 2016 in “Journal of dermatological science” This study found that hair-follicle-associated-pluripotent (HAP) stem cells can be cryopreserved for future use in nerve and spinal cord repair, with human trials being planned.
12 citations
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February 2023 in “Stem Cell Research & Therapy” This study found that injecting hepatocyte growth factor-enhanced hair follicle stem cells into a rat model of ischemic stroke improved recovery by reducing inflammation, protecting the blood-brain barrier, and promoting angiogenesis.
February 2025 in “Infectious Diseases & Immunity” This case report highlights two instances of suspected human herpesvirus 6 reactivation in patients with existing psychiatric disorders, underscoring the need for further research into the relationship between viral reactivation and psychiatric conditions.
1 citations
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June 2019 in “International Journal of Applied Pharmaceutics” In this study, nanostructured lipid carriers for hair split-end repair showed similar efficacy regardless of charge, with negatively charged carriers exhibiting better stability over six months compared to positively charged ones.
April 2024 in “Journal of applied cosmetology” This study found that while hyaluronic acid fillers can enhance facial balance and aesthetics, particularly in the temple area, they carry significant risks like vascular occlusion and blindness, highlighting the need for careful technique and product selection to ensure safety.
September 1997 in “Clinical and Experimental Dermatology”
5 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.
August 2024 in “Clinical and Experimental Dermatology” This study found that while DALL-E 2 can create realistic hair images from text prompts, its accuracy in depicting specific hair disorders, like alopecia areata, often falls short, highlighting the need for AI developers to work with medical experts to improve dermatological applications.