research Clinical Profile of Methotrexate-Resistant Juvenile Localized Scleroderma
Some children with localized scleroderma are rarely resistant to methotrexate, and no common profile for resistance was found.
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research In Situ Labeling of DNA Reveals Interindividual Variation in Nuclear DNA Breakdown in Hair and May Be Useful to Predict Success of Forensic Genotyping of Hair
In situ DNA labeling in hair can help predict forensic DNA analysis success.
research Trichoscopy in Unveiling the Triad of Netherton Syndrome
Trichoscopy helps accurately diagnose Netherton syndrome, often mistaken for atopic dermatitis.
research The Hair Transplant Megasession Technique: A Review
Hair transplant megasessions are safe up to 1500 grafts but larger sessions have more risks and challenges.
research Effect of Metformin Therapy on Clinical and Hormonal Indices of Patients with Polycystic Ovary Syndrome
Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.
research Influence of Substance P on Cultured Sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Studies of Normal Moult and Artificially Induced Regeneration of Pelage in Peromyscus
Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.
research Failure of Intercellular Adhesion in Hair Fibers Regarding Hair Condition and Strain Conditions
Hair breaks differently when wet or dry and is affected by its condition and treatments like perms and bleaching.
research Potential Relationship Between the Canonical Wnt Signaling Pathway and Expression of the Vitamin D Receptor in Alopecia
Targeting the Wnt pathway might help treat hair loss.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Natural Hair Recipe: Evaluation of Natural Preparations for Hair Loss Treatment
The natural hair treatment with Cantharidin works best for hair loss.
research Comparison of Clinical and Laboratory Characteristics of Cases with Polycystic Ovarian Syndrome Based on Rotterdam’s Criteria and Women with Only Oligo/Anovulation or Hirsutism
Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity
Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
research Side Effects of Sodium Valproate During Long-Term Treatment in Epilepsy
Long-term sodium valproate treatment for epilepsy generally caused mild and temporary side effects.
research Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway
Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
research Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study
Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.
research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research A Single-Center Retrospective Study Evaluating the Efficacy of Intravenous Methylprednisolone Pulse Therapy for 113 Patients With Alopecia Areata
Intravenous methylprednisolone helped over half of alopecia areata patients regrow hair, but many relapsed.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
research Androgenetic Alopecia
research Neuroimaging of Sleep and Depression
Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.
research Hair Loss as a Side Effect of Quetiapine: A Clinical Case Report
Quetiapine may cause hair loss.
research Accumulations of Calcium and Phosphorus in the Core of Hairs from Taklamakan Desert Mummies
Mummy hair from the Taklamakan desert has calcium and phosphorus inside.
research A Case of Encephalocraniocutaneous Lipomatosis
The document reports a rare case of ECCL with a new association with optic disc colobomas.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Allergic Contact Dermatitis from Minoxidil
Minoxidil can cause allergic reactions, but testing helps identify the cause.
research Management of Endocrine Disease: Hyperandrogenic States in Women - Pitfalls in Laboratory Diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research Trichotillomania: A Review of Impulse-Control Disorder and Treatment Options
Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.