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Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

New treatments for male hypogonadism are effective and should be personalized.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Both estrogens and androgens are important for health in both males and females.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Polyamines help fix DNA damage accurately in cells.

Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Mouse genital development depends on male or female hormones for specific features.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.