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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The Rotterdam Study aims to understand various diseases in older adults.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair loss can cause low self-esteem, anxiety, and depression in men.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Minoxidil effectively lowers blood pressure with few side effects.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Current treatments for alopecia show no significant long-term benefits.