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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Insulin resistance linked to obesity may increase COVID-19 severity.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

Researchers found two new genetic variants linked to Alzheimer's disease.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Darkened knuckles can be an early sign of insulin resistance.

PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.

Women with PCOS have lower amylin levels, which are not related to their body weight.

Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

The document recommends a team-based approach and personalized care for managing diabetes in teenagers.