research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
Search
for
Sort by
Research
30-60 / 1000+ results 
research Association of DNA Damage with Vitamin D and Hair Heavy Metals in Obese Women
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
research Acknowledging the Clinical Heterogeneity of Lupus Erythematosus
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Side Effects of Common Acne Treatments
Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
research Anthralin (Dithranol) in Dermatology
Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
research The Nutritional Biochemistry of Wool and Hair Follicles
Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder
Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
research Lichen Planus Pigmentosus and Its Variants: Review and Update
Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.
research Management of Acne
Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
research Role of Androgens in Female-Pattern Androgenetic Alopecia, Either Alone or Associated with Other Symptoms of Hyperandrogenism
Androgens significantly affect female hair loss, and hormonal treatments may help.
research Scalp Hair Characteristics in the Newborn Infant
Assessing newborn scalp hair can reveal important health information.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Treatment Options for Alopecia
The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
research Stem Cell Identification: In Vivo Lineage Analysis Versus In Vitro Isolation And Clonal Expansion
In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.
research Severe Steroid-Dependent Idiopathic Angioedema with Response to Rituximab
A woman with severe angioedema improved significantly after treatment with rituximab.
research Androgenic Effect of Testosterone and Its Metabolites in Relation to Their Biotransformation in the Skin
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research A Disease-Modifying Approach for Advanced Hidradenitis Suppurativa: A Case Report
Combination therapy helped patient with advanced Hidradenitis Suppurativa achieve remission.
research Acne and Its Management
Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.
research Into the Redox Control: N-Acetyl-Cysteine Pleiotropic Effects from the Laboratory to Clinical Applications
N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.
research Metabolism of Finasteride in Rat Hepatic Microsomes: Age and Sex Differences and Effects of P450 Inducers
Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.
research Perspectives on Dermatopathology
Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.
research Reporting on Adverse Clinical Events
The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
research Cutaneous Lupus Erythematosus: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society
The Polish Dermatological Society recommends personalized treatment for cutaneous lupus, including lifestyle changes, medications, and monitoring, with specific drugs for severe cases.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Safety of Dermatologic Medications in Pregnancy and Lactation
Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.
research Use of Silver in the Prevention and Treatment of Infections: A Review
Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
research Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research A Review of Diagnosis and Treatment of Acne in Adult Female Patients
Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.