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Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

The document explains various skin conditions and their treatments.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

CDP is crucial for lung and hair follicle cell development.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Certain drugs change freshwater snail shells to a "banana" shape.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.