research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
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research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research Effect of Thioredoxin Reductase 1 on Glucocorticoid Receptor Activity in Human Outer Root Sheath Cells
Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
research Dienogest
Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Frontiers in the Neuroendocrine Controls of Hair Growth
Hair growth and health are influenced by stress and hormones.
research A Practical Approach to Feline Symmetrical Alopecia
The conclusion is to thoroughly test for causes of cat hair loss and treat accordingly, considering medication only after serious conditions are ruled out.
research Severe Impact of Late Diagnosis of Congenital Adrenal Hyperplasia on Gender Identity, Sexual Orientation, and Function: Case Report and Review of the Literature
Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.
research Real-Life Experience with Belimumab in Systemic Lupus Erythematosus: Control of Disease Activity and Flares in a Multicenter Cohort
Belimumab effectively controls SLE disease activity and reduces steroid use.
research Mechanisms of Tolerance and Potential Therapeutic Interventions in Alopecia Areata
Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
research Hirsutism
Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research Androgen Replacement Therapy in Women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice
taVNS reduces vitiligo symptoms in mice.
research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus
Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
research Hypersensitivity Diseases in Horses: Clinical Signs, Diagnosis, and Treatment
The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research Medicinal Plants with Traditional Use: Ethnobotany in the Indian Subcontinent
Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.
research Micro-Current Stimulation Has Potential Effects of Hair Growth Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model
Micro-current stimulation may promote hair growth more effectively than standard treatments.
research The Expanding Impact of T-Regulatory Cells in Skin Health
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Th22 Is the Effector Cell of Thymosin β15-Induced Hair Regeneration in Mice
Th22 cells are essential for Tβ15-induced hair growth in mice.
research Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies
Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
research Focal Alopecia in Dogs
Focal alopecia in dogs has many causes and requires various tests for accurate diagnosis and treatment.
research Androgen Treatment in Women
Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
research Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling
The study found key genes and pathways involved in cashmere goat hair growth stages.